Xunce Technology’s Revenue Surges 449% Half-on-Half: Is a Structural Revaluation to a Hundred-Billion Market Cap Camp on the Horizon? ACN Newswire

Xunce Technology’s Revenue Surges 449% Half-on-Half: Is a Structural Revaluation to a Hundred-Billion Market Cap Camp on the Horizon?

HONG KONG, Mar 27, 2026 - (ACN Newswire) - As AI accelerates into the inference era, enterprise-grade AI is achieving large-scale deployment, driving an exponential surge in Token consumption and ushering data demand into a new development stage. Against this backdrop, high-quality, structured and scenario-specific professional data has become critical for enterprises to forge core strategic competitiveness in the era of AI.As a leading provider of AI real-time data infrastructure and analysis services in China, Xunce Technology is rapidly solidifying its core position in AI data, driven by industry tailwinds, full-chain technological capabilities and diversified growth engines. Amid the unfolding landscape of the intelligent economy, this ten-year industry stalwart is entering a pivotal window for structural revaluation.Token Value Restructuring: Making Every Data Access Quantifiable and MonetizableFounded in 2016, Xunce Technology has built a full-chain technological system spanning data acquisition, cleansing, standardization, real-time computing and large- model optimization over a decade of development. With AI Data Agent at its core, the Company specializes in millisecond-level real-time data processing, serving a diversified portfolio of industries including finance, urban governance, high-end manufacturing, healthcare, robotics, satellite applications, low-altitude economy, electric power, power grids and energy.As the era of AI inference unfolds, Token is evolving from mere “fuel” to a form of “hard currency”. Maximizing the value of each individual Token has emerged as a central challenge in the large-model inference era. Today, general-purpose large models typically rely on a “computing power for precision” approach, where every inference run generates substantial wasteful Token consumption. Should inference fail, all Tokens expended in the process are lost entirely, which is a common pain-point plaguing general AI systems.By contrast, vertical AI solutions equip general large language models with an external industry “brain” powered by domain-specific data. At its core, such solutions optimize inference logic via business-aware models, enabling upfront task feasibility validation and eliminating Token waste at the source. With deep expertise in professional vertical domain data modeling, Xunce Technology leverages its extensive portfolio of high-quality, scenario-specific proprietary data to act as an “efficiency multiplier” for every Token invocation. This structure translates Token consumption into higher-precision outputs while securing maximal result certainty. Crucially, the Company is developing full-chain capabilities spanning data metering, pricing and settlement, enabling quantifiable and monetizable measurement for every data access. By elevating per-unit Token efficiency, it delivers enhanced business value to enterprise clients.Aligned with this strategy, Xunce’s platform features a “LEGO-inspired” modular architecture, enabling clients to flexibly compose modules tailored to their specific needs. This “assemble-on-demand, adapt-in-real-time” design fosters deep and long-term customer stickiness. The Company also employs a highly flexible pricing framework, with fees structured around module count, processing throughput and other key metrics. Supported by subscription, transaction-based and Token-based payment models, its pricing mechanism precisely aligns with diverse client demands.Currently, Xunce Technology is fully building a full-chain data measurement and settlement system. It is exploring pricing mechanisms tied to large model inference frequency and module usage count, allowing customers to pay for effective Tokens rather than raw computing power consumption.Inflection Point Reached, Profitability ConfirmedDriven by Token value restructuring and innovative business models, Xunce Technology has delivered robust performance and reached a historic inflection point. In H2 2025, the Company posted an adjusted net profit of RMB 50 million, achieving its first positive profitability. Meanwhile, revenue rose from RMB 197.85 million in H1 2025 to RMB 1,086.81 million in H2, representing a 449.32% quarter-on-quarter surge. Amid rapid business expansion, the Company has witnessed a substantial improvement in profitability.Explosive Revenue GrowthReturn to Profit in H2Doubled ARPU & Per Capita GrowthImproved Cash Flow & Operating Metrics+103% Y/YNarrowed by 33%+105% Y/YSignificant Improvement2025 full-year revenue YoY growth2025 full-year adjusted net loss2025 ARPU YoY growth2025 net operating cash flow+449% H/HRMB 50 million+135% Y/YAmple cash on hand in 20252025 H2 revenue HoH growth2025 H2 adjusted net profit2025 per capita revenue YoY growthAverage collection period decreased in 2025For the full year, the Company posted total operating revenue of RMB 1,284.66 million, representing a substantial year-on-year increase of 103.28% and successfully breaking the key milestone of RMB 1 billion in revenue. This signifies that the Company has evolved from an early-stage, technology-driven startup into a new era of platform-based development with scalable and replicable business models.Furthermore, the Company’s combined gross proceeds for 2025 amounted to approximately RMB 792.08 million, representing a substantial increase of 63.44% compared to approximately RMB 484.63 million in the previous year. In terms of adjusted net loss, after deducting one-off non-recurring gains and losses, the Company’s adjusted net loss for 2025 was RMB 54.84 million, representing a significant narrowing of 33% from RMB 82.37 million in 2024.Notably, the Company achieved combined gross margin of 62% in 2025, exceeding that of Cambricon (55%), a leading AI chip provider, and far outpacing general large- model developer Minimax (25.4%). This underscores its high-value strategic positioning and resilient business model in the AI data infrastructure sector.In terms of R&D investment, Xunce Technology has also maintained efficient growth conversion. In 2025, the Company’s R&D expenditure reached RMB 450.44 million, with R&D expenses accounting for 48% of revenue, driving a 105% year-on-year increase in operating revenue. For comparison, Minimax’s R&D expenditure accounted for as high as 219% of its revenue, with a revenue growth rate of 159%. Xunce achieved a comparable expansion pace with a lower R&D intensity.As revenue scale continues to expand and gross margin in new industries gradually stabilize, the Company’s short-term objective is to achieve an inflection point in adjusted net profit. Looking ahead, as the industries already deployed enter a period of margin stabilization and Token-based payment and revenue-sharing models gain accelerated traction, its net profit is poised to improve at an accelerated rate.Driven by Diversified Growth Engines, Business Structure Continuously OptimizedThe robust revenue growth is not accidental, but underpinned by Xunce Technology’s multi-dimensional, systematically structured growth framework.Accelerate cross-industry replication. The Company currently covers 9 major industries, benchmarking Palantir’s 17 industries and leaving ample room for horizontal expansion. Xunce Technology is rapidly deepening its presence in key national strategic sectors such as asset management, telecommunications, electric power, urban management, high-end manufacturing, healthcare, energy, robotics training platforms and commercial aerospace. For each new industry, the Company first completes industry-specific data accumulation over 3 to 5 years, enabling rapid replication and scaled deployment across peer customers thereafter.The business model fosters deep customer value enhancement. As customers evolve from single-module adoption to multi-module deployment, and from pilot trials to full integration into core business workflows, substantial upside potential in ARPU remains. By synergistically lifting Token invocation volume, module usage count and per-Token value, the Company will unlock a new dimension of growth.Steadily expand overseas business and establish a global layout. The Company targets raising its overseas revenue share to 10% to 15% in 2026, and will further escalate its globalization strategy during 2027 and 2028, unlocking new avenues for sustained long-term growth.Cultivate a strategic cooperative ecosystem to forge deep integration with upstream and downstream partners in computing power and algorithms. Xunce Technology is engaging in in-depth collaboration with leading domestic GPU providers and large language model enterprises to build a one-stop solution encompassing “infrastructure computing power, upper-layer applications and data governance,” further solidifying its core position in the AI data infrastructure sector. Pioneer cutting-edge applications to seize commanding heights in future industries. From robotics data platforms to commercial aerospace, low-altitude economy and power grid systems, Xunce Technology has taken the lead in extending AI infrastructure to emerging sectors with stringent demands for real-time performance and operational reliability. Such mission-critical scenarios with ultra-high requirements for data timeliness and stability serve as a rigorous validation of the Company’s technological advantages. The Company will continue to ramp up R&D investment in frontier fields, refine its technical capabilities through high-end application scenarios and unlock new high-growth, high-value growth tracks for long-term development.Evolving from Data Services to Core AI Economy Infrastructure: Building Sustainable Competitive BarriersFrom a macro perspective, the artificial intelligence data sector is witnessing a profound convergence of five defining trends: a surge in demand for real-time, secure, high-quality data in the era of AI Agent; the rise of domain-specific models elevating professional data as a critical enabler for industry-wide intelligent upgrading; standardization of data interfaces driven by next-generation AI operating systems including Open Claw, positioning Xunce Technology as a core data Token provider; Token-based payment emerging as a new paradigm for the data element market; and the implementation of data asset capitalization policies, spurring a sharp rise in enterprises’ mandatory investment in data governance.At the intersection of these five pivotal trends, Xunce Technology has established a robust fundamental logic for sustained long-term growth. The Company has evolved beyond a traditional data infrastructure provider to become a critical “connector” and “enabler” linking large models, computing power and cloud vendors. By integrating upstream models, downstream computing power and horizontal collaboration with cloud vendors, the Company delivers irreplaceable data-centric value to its enterprise clients.The Company stresses that it shares a natural upstream-downstream synergy with general large-model providers, rather than a competitive dynamic. Analogous to the deep collaboration between GPU manufacturers and model developers, the value of Xunce Technology lies in a mutually reinforcing cycle: the wider the adoption of models by its clients, the greater the opportunity for the Company to deliver services and generate incremental value for clients.Notably, in contrast to niche market players offering only isolated modules such as data cleansing or computing engines, Xunce Technology’s core differentiation lies in its full-process coverage and outcome-driven accountability. The Company provides an end-to-end solution spanning data acquisition, cleansing, standardization, modeling, real-time computing and model tuning, ensuring that final data delivered to clients is clean, accurate, real-time and accessible for model invocation at millisecond latency. Furthermore, through deep integration into clients’ private clouds or on-premises environments, the Company acts as a dedicated data steward, fostering exceptional customer stickiness and forging robust, sustainable competitive barriers.Currently, the Company’s product portfolio and solutions feature more than 300 functional modules, covering a full spectrum of scenarios from data infrastructure to upper-layer analytics applications. In 2025, its active paid clients base reached 230, with an outstanding customer retention rate of 90%. ARPU increased substantially from RMB 2.72 million in 2024 to RMB 5.59 million in 2025, representing a year-on-year growth of over 103%.As algorithms become increasingly open-source and computing power tends toward standardization, what truly sets companies apart lies in data — particularly industry data that has undergone sophisticated governance and can effectively empower large models. Backed by a decade of deep industry expertise, Xunce Technology has established a substantial and sustainable competitive barrier in this domain.ConclusionFrom an early-stage private equity tool provider to a cross-industry AI data infrastructure builder, and from a module supplier to a Token-priced core platform, Xunce Technology has remained committed to unlocking data as a scarce, strategic resource that is freely circulable, readily callable and empowered to drive high-quality decision-making.Amid the rapid emergence of new intelligent economic paradigms, the Company stands at the threshold of a fundamental structural revaluation, with the potential to enter the RMB 100-billion market cap camp. It is a competitor to none, but an indispensable partner to all. Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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Application Submitted for LENVIMA(R) (lenvatinib) in Japan Seeking Approval of Additional Dosage and Administration for Combination with WELIREG(R) (belzutifan) for Renal Cell Carcinoma that has Progressed After Chemotherapy JCN Newswire

Application Submitted for LENVIMA(R) (lenvatinib) in Japan Seeking Approval of Additional Dosage and Administration for Combination with WELIREG(R) (belzutifan) for Renal Cell Carcinoma that has Progressed After Chemotherapy

TOKYO, Mar 27, 2026 - (JCN Newswire) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and MSD K.K. (Headquarters: Tokyo, Representative Director: Prashant Nikam, “MSD”), a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, announced today that an application for LENVIMA® (lenvatinib), an orally available multiple receptor tyrosine kinase inhibitor (TKI) discovered by Eisai, has been submitted in Japan for the additional dosage and administration in combination with WELIREG® (belzutifan), the first-in-class oral hypoxiainducible factor-2 alpha (HIF-2α) inhibitor from MSD, for the treatment of unresectable or metastatic renal cell carcinoma that has progressed after chemotherapy.This application is based on the results of the Phase 3 LITESPARK-011 trial evaluating the dual regimen of LENVIMA plus WELIREG for the treatment of patients with advanced renal cell carcinoma (RCC) whose disease progressed on or after treatment with anti-programmed death receptor-1 (PD-1)/ programmed death-ligand 1 (PD-L1) therapy. The data from this trial were presented at the 2026 American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium in February 2026. At a pre-specified interim analysis with a median follow-up of 29.0 months (range, 19.3-49.2), the LENVIMA plus WELIREG combination therapy demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS), one of the primary endpoints, reducing the risk of disease progression or death by 30% (HR=0.70 [95% CI, 0.59-0.84]; p=0.00007) compared to cabozantinib. The safety profile of this combination was consistent with those reported for each agent administered as monotherapy, and no new safety signals were identified.In 2022, approximately 435,000 people worldwide were newly diagnosed with kidney cancer, and about 156,000 people died from the disease. 1 In Japan, it is estimated that roughly 21,000 people were newly diagnosed and about 7,000 died in 2022.2 RCC accounts for approximately 85% of kidney cancers3, and the five-year survival rates for patients with stage III and IV RCC have been reported as 63%–78% and 27%–28%4, respectively, indicating that the disease still has a high unmet medical needs.LENVIMA is approved in combination with KEYTRUDA ® (pembrolizumab) in Japan for the first-line treatment of unresectable or metastatic RCC. WELIREG is approved in Japan for the treatment of unresectable or metastatic RCC that has progressed following cancer chemotherapy. Additionally, supplemental New Drug Applications (sNDA) for the LENVIMA and WELIREG combination therapy for the treatment of adult patients with advanced RCC with a clear cell component following a PD-1 or PDL1 inhibitor has been accepted by the U.S. Food and Drug Administration (FDA), with a PDUFA (Prescription Drug User Fee Act) target action date set for October 4, 2026.Eisai and MSD have been collaborating through the provision of information on LENVIMA in Japan since October 2018, and will work together to expedite the maximization of contribution to patients with cancer.About LENVIMA (lenvatinib)LENVIMA, discovered and developed by Eisai, is an orally available multiple receptor tyrosine kinase inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). LENVIMA inhibits other kinases that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1- 4, the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. In syngeneic mouse tumor models, LENVIMA decreased tumor-associated macrophages, increased activated cytotoxic T cells, and demonstrated greater antitumor activity in combination with an anti-PD-1 monoclonal antibody compared to either treatment alone. LENVIMA has been approved for the indications below.Thyroid cancer- Indication as monotherapy(Approved mainly in Japan, the United States, Europe, China and Asia)Japan: Unresectable thyroid cancerThe United States: The treatment of patients with locally recurrent or metastatic, progressive, radioiodine-refractory differentiated thyroid cancer (DTC)Europe: The treatment of adult patients with progressive, locally advanced or metastatic, differentiated (papillary/follicular/Hürthle cell) thyroid carcinoma (DTC), refractory to radioactive iodine (RAI)Hepatocellular carcinoma- Indication as monotherapy(Approved mainly in Japan, the United States, Europe, China and Asia)Japan: Unresectable hepatocellular carcinomaThe United States: The first-line treatment of patients with unresectable hepatocellular carcinoma (HCC)Europe: The treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have received no prior systemic therapy- Indication in combination with KEYTRUDA (generic name: pembrolizumab) and transarterial chemoembolization (Approved in China)Thymic carcinoma- Indication as monotherapy (Approved in Japan)Japan: Unresectable thymic carcinomaRenal cell carcinoma (In Europe other than the United Kingdom, the agent was launched under the brand name Kisplyx®)- Indication in combination with everolimus(Approved mainly in the United States, Europe and Asia) The United States: The treatment of adult patients with advanced renal cell carcinoma (RCC) following one prior anti-angiogenic therapyEurope: The treatment of adult patients with advanced renal cell carcinoma following one prior vascular endothelial growth factor (VEGF) targeted therapy- Indication in combination with KEYTRUDA(Approved mainly in Japan, the United States, Europe and Asia)Japan: Radically unresectable or metastatic renal cell carcinomaThe United States: The first-line treatment of adult patients with advanced renal cell carcinomaEurope: The first-line treatment of adult patients with advanced renal cell carcinomaEndometrial carcinoma- Indication in combination with KEYTRUDA(Approved mainly in Japan, the United States, Europe and Asia)Japan: Unresectable, advanced or recurrent endometrial carcinoma that progressed after cancer chemotherapyThe United States: The treatment of patients with advanced endometrial carcinoma that is pMMR or not microsatellite instability-high (MSI-H), as determined by an FDA-approved test, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiationEurope: The treatment of adult patients with advanced or recurrent endometrial carcinoma (EC) who have disease progression on or following prior treatment with a platinum-containing therapy in any setting and are not candidates for curative surgery.About WELIREG (belzutifan)WELIREG, Merck & Co., Inc., Rahway, NJ, USA’s, known as MSD outside of the United States and Canada, first-in-class hypoxia-inducible factor 2 alpha (HIF-2α) inhibitor, is an orally administered small-molecule designed to reduce transcription and expression of HIF-2α target genes associated with cellular proliferation, angiogenesis and tumor growth. By inhibiting HIF-2α signaling, WELIREG aims to disrupt key pathways certain tumors may use to adapt to low-oxygen conditions, including those that help promote abnormal blood vessel formation and support tumor survival. WELIREG has demonstrated antitumor activity in certain von Hippel-Lindau (VHL) diseaseassociated tumors, renal cell carcinoma and in pheochromocytoma or paraganglioma. As part of a broader clinical program, Merck & Co., Inc., Rahway, NJ, USA continues to research WELIREG monotherapy and combination approaches for people with genitourinary, breast and gynecologic cancers across a range of treatment settings to further define where HIF-2α inhibition may provide clinical benefit and to better understand which patients are most likely to respond. WELIREG has been approved in Japan for the treatment of certain von Hippel–Lindau (VHL) disease–associated tumors, as well as for unresectable or metastatic renal cell carcinoma that has progressed after chemotherapy.LITESPARK-011 ResultsData from LITESPARK-011 (ClinicalTrials.gov, NCT04586231) were presented at the ASCO GU Symposium held in February 2026. LITESPARK-011 is a randomized, open-label Phase 3 trial (ClinicalTrials.gov, NCT04586231) evaluating WELIREG in combination with LENVIMA compared to cabozantinib for the treatment of patients with advanced clear cell RCC that has progressed on or after anti-PD-1/L1 therapy. The dual primary endpoints are progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST v1.1) as assessed by blinded independent central review (BICR), and overall survival (OS). Secondary endpoints include objective response rate (ORR) per RECIST v1.1 as assessed by BICR, duration of response (DOR) per RECIST v1.1 as assessed by BICR, and safety. The trial enrolled 747 patients who were randomized to receive WELIREG (120 mg orally once daily) plus LENVIMA (20 mg orally once daily) or cabozantinib (60 mg orally once daily).At a pre-specified second interim analysis with a median follow-up of 29.0 months (range, 19.3- 49.2), WELIREG plus LENVIMA demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint of PFS, reducing the risk of disease progression or death by 30% (HR=0.70 [95% CI, 0.59-0.84]; p=0.00007) compared to cabozantinib. For WELIREG plus LENVIMA, the median PFS was 14.8 months (95% CI, 11.2-16.6) versus 10.7 months (95% CI, 9.2-11.1) for cabozantinib. A trend toward improvement in overall survival (OS), the trial’s other primary endpoint, was also observed for WELIREG plus LENVIMA (HR=0.85 [95% CI, 0.68-1.05]; p=0.06075). The median OS was 34.9 months (95% CI, 27.5-NR) for WELIREG plus LENVIMA versus 27.6 months (95% CI, 24.0-31.4) for cabozantinib. The trial is continuing, and OS will be evaluated at a subsequent analysis per the clinical trial protocol. Regarding secondary endpoints, at the first interim analysis with a median follow-up of 19.6 months (range, 9.9-39.8), WELIREG plus LENVIMA met ORR, demonstrating a statistically significant improvement compared to cabozantinib. A confirmed ORR of 52.6% (95% CI, 47.3-57.7) was observed for WELIREG plus LENVIMA versus 39.6% (95% CI, 34.6-44.8) for cabozantinib. At the second interim analysis with a median follow-up of 29.0 months, the median DOR was 23.0 months (95% CI, 2.0-44.3+) for WELIREG plus LENVIMA versus 12.3 months (95% CI, 1.8+-35.9+) for cabozantinib. WELIREG plus LENVIMA was administered to 370 patients and cabozantinib was administered to 371 patients. Grade ≥3 treatment-related adverse events (TRAEs) occurred in 71.6% of patients receiving WELIREG plus LENVIMA versus 65.8% of patients receiving cabozantinib. Adverse events led to treatment discontinuation in 11.1% of patients receiving WELIREG plus LENVIMA and in 11.3% of patients receiving cabozantinib, respectively. Serious adverse events were observed in 51.6% of patients receiving WELIREG plus LENVIMA versus 43.9% of patients receiving cabozantinib, and AEs led to death in 5.4% of patients (two were treatment-related: thrombotic microangiopathy [n=1] and pneumonitis [n=1]) versus 3.2% (one was treatment-related: hemoptysis [n=1]) of patients, respectively.About the Eisai and Merck & Co., Inc., Rahway, NJ, USA Strategic CollaborationIn March 2018, Eisai and Merck & Co., Inc., Rahway, NJ, USA through an affiliate, entered into a strategic collaboration for the worldwide co-development and co-commercialization of LENVIMA. Under the agreement, the companies jointly develop, manufacture and commercialize LENVIMA, both as monotherapy and in combination with Merck & Co., Inc., Rahway, NJ, USA’s anti-PD-1 therapy, KEYTRUDA, and HIF-2α inhibitor, WELIREG.Eisai’s focus on cancerEisai acknowledges “Oncology” as one of its key strategic areas, and will continue to focus on the discovery and development of anti-cancer drugs within drug discovery domains including “microenvironment”, “protein integrity and homeostasis”, and “cell lineage and cell differentiation” under the Deep Human Biology Learning (DHBL) drug discovery and development organization. Eisai aspires to discover innovative new drugs with new targets and mechanisms of action from these domains, with the aim of contributing to the cure of cancers.6. About EisaiEisai’s Corporate Concept is “to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides.” Under this Concept [also known as our human health care (hhc) Concept], we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, our continued commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), is demonstrated by our work on various activities together with global partners. For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai Co., Ltd.), us.eisai.com (for U.S. headquarters: Eisai Inc.) or www.eisai.eu (for Europe, Middle East, Africa, Russia, Australia, and New Zealand headquarters: Eisai Europe Ltd.), and connect with us on X (U.S. and global), LinkedIn (for U.S. and EMEA) and Facebook (global).Merck & Co., Inc., Rahway, NJ, USA’s Focus on CancerEvery day, we follow the science as we work to discover innovations that can help patients, no matter what stage of cancer they have. As a leading oncology company, we are pursuing research where scientific opportunity and medical need converge, underpinned by our diverse pipeline of more than 25 novel mechanisms. With one of the largest clinical development programs across more than 30 tumor types, we strive to advance breakthrough science that will shape the future of oncology. By addressing barriers to clinical trial participation, screening and treatment, we work with urgency to reduce disparities and help ensure patients have access to high-quality cancer care. Our unwavering commitment is what will bring us closer to our goal of bringing life to more patients with cancer. For more information, visit https://www.merck.com/research/oncologyAbout MSDAt MSD (the name by which Merck & Co., Inc., Rahway, NJ, USA, is known outside of the United States and Canada), we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.msd.co.jp and connect with us on Facebook, Twitter, and YouTube.Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, et al. (2024) Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Available from: https://gco.iarc.who.int/media/globocan/factsheets/cancers/29-kidney-fact-sheet.pdf, accessed 27 Mar 2026.Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, et al. (2024) Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer, Available from: https://gco.iarc.who.int/media/globocan/factsheets/populations/392-japan-fact-sheet.pdf, accessed 27 Mar 2026.National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Kidney Cancer. 2025; 2026 Version 1. Rose TL and Kim WY. Renal cell carcinoma: a review. JAMA. 2024 Sep 24;332(12):1001– 10.Media InquiriesEisai Co., Ltd.Public Relations DepartmentTEL: +81 (0)3-3817-5120MSD K.K.Communications DivisionTatsuro MuraseTEL: +81 (0)70-8700-0112 Copyright 2026 JCN Newswire. All rights reserved. www.jcnnewswire.com
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Hitachi and MUFG Bank expand NextGen model to finance vehicles and charging infrastructure for decarbonized mobility JCN Newswire

Hitachi and MUFG Bank expand NextGen model to finance vehicles and charging infrastructure for decarbonized mobility

TOKYO, Mar 27, 2026 - (JCN Newswire) - Hitachi, Ltd. (TSE: 6501, “Hitachi”) and MUFG Bank, Ltd. (“MUFG Bank”), a consolidated subsidiary of Mitsubishi UFJ Financial Group, Inc. (TYO: 8306, “MUFG”) today announced a new Memorandum of Understanding (MoU) to expand NextGen, their business co-creation model. Building on their collaboration launched in May 2024*1 and further developed as announced in May 2025*2 , NextGen combines Hitachi’s technology and operational expertise with MUFG’s financial capabilities to accelerate the transition to decarbonized mobility.*1 MUFG’s Business Co-Creation and Investment into UK Battery as a Service project by Hitachi ZeroCarbon May 2024*2 Hitachi ZeroCarbon and MUFG unite technology expertise with financial support to accelerate fleet electrification May 2025NextGen was initially validated through a UK pilot project with First Bus, where the parties collaborated via a special purpose vehicle (SPV) to support the procurement and operation of electrification assets under a Battery-as-a-Service model. This expanded MoU extends NextGen beyond battery-focused structures, enabling broader and more scalable deployment across additional markets outside the UK and across a wider range of asset classes. These include emobility assets such as electric vehicles and charging infrastructure, associated energy management systems, and potentially extending to energy hubs supporting industrial assets, power grids and data centers.Hitachi and MUFG Bank will also develop and scale SPV structures to finance decarbonized mobility assets for fleet and transport operators. This approach removes capital constraints and accelerates implementation, enabling operators to focus on their core transport services. From Hitachi’s side, the initiative is led by its Strategic SIB Business Unit, bringing together expertise from across Hitachi including Hitachi Energy, as ‘One Hitachi’. Hitachi will also provide managed services for asset performance and lifecycle optimization, supported by data-driven solutions from Hitachi ZeroCarbon. Through this initiative, Hitachi aims to further advance and streamline mobility and charging infrastructure operations by expanding HMAX by Hitachi, a suite of next-generation solutions that embodies Lumada 3.0, differentiated by deep domain knowledge and AI.Electrifying commercial transport at pace will require an unprecedented deployment of vehicles, charging and energy infrastructure - alongside innovative financing models to support it. Global investment in electrified transport reached around US$750 billion in 2024, making it the largest segment of the energy transition worldwide*3 - yet many fleet operators face limited access to capital and the operational complexity of transitioning at scale. Against this backdrop, Hitachi and MUFG Bank aim to expand NextGen as a repeatable model to accelerate implementation by combining structured asset financing with managed services and data-driven optimization.*3 Sources: BloombergNEF’s Energy transition Investment Trends 2025In demonstration of the expanded pipeline, Hitachi ZeroCarbon and MUFG Bank have also entered into an MoU with Boreal Norge AS and its subsidiary Boreal Buss AS, one of Norway’s primary transport operators, providing transport services across several counties and employing around 3,000 employees across its fleet, which includes over 850 buses and 35 ferries. The parties will explore how they can support Boreal’s transition planning, de-risk operations, optimize services and strengthen competitiveness as concessions evolve.Jun Taniguchi, Senior Vice President and Executive Officer, CEO of Strategic SIB Business Unit, at Hitachi, Ltd. said:“We are delighted to advance this partnership which combines Hitachi’s deep expertise in social infrastructure and digital technologies with MUFG Bank, Ltd.’s financial strength to accelerate the transition to a decarbonized society. By improving the performance of assets such as batteries and charging infrastructure through Hitachi’s digital services led by HMAX, we can truly help customers optimize the total cost of ownership. This partnership embodies our One Hitachi approach, leveraging our diverse capabilities across the Group to support our customers in achieving their net-zero ambitions.”Masakazu Osawa, Senior Managing Executive Officer Chief Executive, Japanese Corporate & Investment Banking Business Unit of MUFG Bank, Ltd., said:“Building on MUFG’s Business Co‑Creation and Investment approach, this collaboration with Hitachi aims to create value through strategic partnerships that improve society and the environment. For the global EV market, our focus is not only on strengthening Hitachi’s leading position in Battery as a Service, but also on fostering a holistic value chain — including second‑ life battery markets — that supports the acceleration of electric mobility and the achievement of 2050 net‑zero targets. Together with our partners, we are committed to co‑creating sustainable businesses that become a driving force for progress worldwide.”Nikolai Knudsmoen Utheim, Group CEO, Boreal Norge AS said:“Our priority has always been to deliver first-class transport services to our customers, whether that’s on the road, rail or over water. In exploring how we can unlock the power of electrified fleets, we can not only deliver more sustainable operations, but upgrade our infrastructure and thread technology across our entire business model for more efficient, smart transport and energy management.”About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT (Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries – and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024 (ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com.About MUFGMitsubishi UFJ Financial Group, Inc. (MUFG) is one of the world’s leading financial groups. Headquartered in Tokyo and with over 360 years of history, MUFG has a global network with approximately 2,000 locations in more than 40 countries. The Group has about 150,000 employees and offers services including commercial banking, trust banking, securities, credit cards, consumer finance, asset management, and leasing. The Group aims to “be the world’s most trusted financial group” through close collaboration among our operating companies and flexibly respond to all of the financial needs of our customers, serving society, and fostering shared and sustainable growth for a better world. MUFG’s shares trade on the Tokyo, Nagoya, and New York stock exchanges. For more information, visit https://www.mufg.jp/english.About BorealBoreal is a leading mobility provider, operating buses, fast ferries, passenger ferries and trams in Norway and Sweden. We remain firmly committed to our societal mission of encouraging more people to travel collectively. At the same time, we are more than public transport. As the only company operating buses, ferries, fast ferries, trams and tourism services, we deliver integrated mobility solutions and travel experiences. Although Boreal is a young company in name, its heritage extends back more than 150 years. The company has around 3,000 employees and is headquartered in Stavanger, Norway. Copyright 2026 JCN Newswire. All rights reserved. www.jcnnewswire.com
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Analogue 2025 Annual Results Profit Attributable to Owners of the Company Increases 23.5% to HK$167.0 Million ACN Newswire

Analogue 2025 Annual Results Profit Attributable to Owners of the Company Increases 23.5% to HK$167.0 Million

HONG KONG, Mar 27, 2026 - (ACN Newswire) - Analogue Holdings Limited (“Analogue” or the “Company”, together with its subsidiaries, the “Group”) (stock code: 1977), a leading provider of electrical and mechanical (“E&M”) engineering solutions, and information and communications technology services for smart cities, today announced its annual results for the year ended 31 December 2025 (“the Year” or “FY2025”) with net profit growth, contracts-in-hand achieving another record high and order intake more than doubled, providing a solid business foundation for the coming three years and beyond.Financial Highlights- Profit attributable to owners of the Company increased 23.5% to HK$167.0 million.- Contracts-in-hand surged 61.8% to HK$17,878.7 million, hitting another record-high, made possible by a 113.7% increase in order intake to HK$12,913.6 million during the Year.- The intake of new maintenance contracts for housing programmes, environmental projects and lifts and escalators increased 51.4% to HK$1,669 million, reinforcing the recurring revenue stream.- The Group maintained a strong cash position, with bank balances and cash of HK$1,020.8 million and gearing ratio reduced to 10.1% for FY2025 from 26.2%.- The Board has resolved to pay a second interim dividend of HK2.9 cents per share. Total dividend for the year amounted to HK5.5 cents per share with 25.6% increment year-on-year.Chairman Dr Mak Kin Wah said, “The Year 2025 saw profound changes around the world, with challenges and yet also opportunities. Our Group has continued to stride forward: upholding what we commit by delivering the fundamentals well, striving for continuous improvement to make transformation actionable, investing in technology advancement and productivity, and bringing Hong Kong’s engineering excellence to the world. We are pleased to report that the Group achieved profit growth, secured a record level of contracts-in-hand, and continued to build on our international market presence. These accomplishments highlight our distinctive comprehensive capability across diverse business segments, our commitment to excellence, and our leadership in advanced engineering techniques.”“Supported by strong cashflow, we are in a strong position to take on additional work where appropriate and to seize high-value opportunities as they arise. We will continue to stay agile and focused on capturing opportunities across our broad portfolio, build on our competitive strengths through continuous improvement, and reinforce the use of innovative solutions that enhance quality, safety and performance. We remain steadfast in our commitment to our customers, recognising that this is fundamental to earning their trust and cultivating enduring, strategic partnerships. Guided by our motto – ‘We Commit. We Perform. We Deliver’ – we will continue to maximise value for customers, shareholders, suppliers and stakeholders, while contributing to the communities we serve.”Business Review: Building Services- This segment remains the largest revenue contributor, with revenue reaching HK$3,279 million.- Contracts-in-hand reached a record-high level of HK$8,297 million with the total value of new contracts secured in FY2025 doubled to HK$6,470 million. The Group’s competitive edge in multidisciplinary packaged projects and its industry leadership in innovative MiMEP and other new engineering techniques helped it to secure major contracts.- With strategic investments to accelerate innovation and modern manufacturing facilities in Zhuhai and Hong Kong, the Group continues to lead in MiMEP and DfMA technologies.- Following the successful acquisition of a property management licence, the Group expanded its business to deliver integrated solutions across the entire building lifecycle. This new capability, spanning construction, maintenance, operations and long-term facility management, creates a potential revenue stream that complements core services.- Through continuous development of innovative technologies and operational optimisation, the segment is positioning itself to maintain the market competitiveness while exploring opportunities in other markets in Southeast Asia.Environmental Engineering- This segment achieved record-high contracts-in-hand and order intake, increasing 86.9% and 253.7% to HK$8,094 million and HK$5,355 million respectively. Segment revenue also increased by 18.0% year-on-year to HK$1,591 million.- The segment maintained active tendering throughout the period and was awarded significant contracts, including contracts of a record-breaking value to relocate sewage treatment works in Sha Tin to caverns, sewage pumping station at Ma On Shan and more.- Formed a joint venture company in Qingyang city to explore the operation and maintenance business in the Chinese Mainland.- Explored project opportunities in Asia and the Middle East and the expansion of its expert services into Europe.Information, Communications and Building Technologies (“ICBT”)- Segment revenue remained at HK$630 million. Contracts-in-hand totalled HK$852 million at the year end, and order intake was HK$523 million during the Year.- This segment continued to reinforce its leadership in green and intelligent building solutions under the DigiFusion brand, to enable the development of smarter, more sustainable urban environments.- Continued to leverage ATAL Tower as a platform for developing innovative technologies and broaden its technological capabilities through strategic collaborations with leading manufacturers in the Chinese Mainland and around the world, to strengthen its ability to deliver scalable, high-performance solutions across a wide range of sectors.Lifts and Escalators- Revenue and order intake increased 11.0% to HK$587 million and by 3.2% to HK$566 million respectively.- Transel Elevator & Electric Inc. (TEI), the associate company in the United States (US), secured a contract for the world-class vertical transportation system in the iconic 56-storey luxury hotel skyscraper on the border of Times Square in New York. TEI also further strengthened its market position by extending its footprint into the Southeastern part of US.- Actively built on its presence in the UK and broadened its network across other international markets, reinforcing its global ambitions in vertical transportation solutions.- Machine-Room-Less lift products continued to gain traction in key international markets- Streamlined the manufacturing processes of Nanjing factory, broadened its product portfolio and strengthened the overall product quality, aligning with the Group’s global vision and reaffirming its commitment to delivering reliable, high-performance vertical transportation solutions.For further details of the 2025 Annual Results, please refer to the announcement filed with The Stock Exchange of Hong Kong Limited.About Analogue Holdings LimitedEstablished in 1977, Analogue Holdings Limited is a leading provider of electrical and mechanical (“E&M”) engineering solutions and information and communications technology (“ICT”) services for smart cities, with headquarters in Hong Kong and operations in the Chinese Mainland, Macau, the United States, the United Kingdom, Germany, Singapore and Malaysia. Serving a wide spectrum of customers from public and private sectors, the Group provides multidisciplinary and comprehensive E&M engineering and technology services in four major segments, including Building Services, Environmental Engineering, Information, Communications and Building Technologies (“ICBT”) and Lifts & Escalators.The Group also manufactures and sells lifts and escalators internationally and has entered into an alliance with Transel Elevator & Electric Inc. (“TEI”), one of the largest independent lifts and escalators companies in New York, the United States. The Group’s associate partner, Nanjing Canatal Data-Centre Environmental Tech Co., Ltd. (603912.SS), specialises in manufacturing of precision air conditioners. Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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Behind the 449% Sequential Revenue Growth: Xunce Technology, Accelerates Its Embrace of the Token Economy

EQS Newswire / 27/03/2026 / 18:36 UTC+8 On March 27, 2026, Hong Kong-listed Xunce Technology (03317.HK) released its 2025 annual results, delivering a standout performance that captured market attention. The company achieved full-year revenue of RMB 1.285 billion, representing year-on-year growth of 103.28%, crossing the RMB 1 billion revenue threshold. Adjusted net loss narrowed to RMB 54.85 million, a significant improvement of 33.31% from the previous year. More importantly, the company achieved adjusted net profit of RMB 50.13 million in the second half of 2025, marking its first semi‑annual profitability and confirming a clear inflection point. In terms of growth trajectory, first‑half revenue was RMB 198 million, while second‑half revenue surged to RMB 1.087 billion, a 449.32% sequential increase. This explosive growth closely aligns with the concentrated release of enterprise demand for real‑time data as AI models entered a phase of large‑scale deployment. As the AI industry shifts its focus from "model training" to "inference at scale," the strategic importance of data infrastructure is being fundamentally rewritten. Behind these results lies Xunce Technology's value realization as a core player in AI‑driven real‑time data infrastructure, signaling the arrival of a new era driven by the token economy. Financial Inflection Point: More Than Growth – A Qualitative Shift What makes Xunce's 2025 results particularly compelling is not just the revenue growth, but the simultaneous improvement in profitability and growth trajectory. The shift in profitability carries even greater significance. Full‑year adjusted net loss narrowed to RMB 54.85 million, a 33.41% improvement over 2024. Looking at the second half alone, the company achieved adjusted net profit of RMB 50.14 million – a sharp reversal from the RMB 105 million loss in the first half – marking its first semi‑annual profit. This demonstrates that the company's business model has successfully navigated the transition from scale expansion to profit generation. From a financial structure perspective, as of the end of 2025, total assets reached RMB 3.172 billion, net assets stood at RMB 2.42 billion, and cash and cash equivalents reached RMB 1.084 billion, an increase of approximately 216% year‑on‑year, providing ample "ammunition" for future strategic investments. The asset‑liability ratio was only 1.51%, reflecting minimal leverage and a very solid financial foundation. In terms of operational efficiency, revenue per employee jumped from RMB 1.22 million in 2024 to RMB 2.87 million, an increase of 135.25%, effectively doubling workforce productivity. Customer ARPU also increased from RMB 2.72 million to RMB 5.59 million, up 105.04% year‑on‑year, demonstrating a growing ability to deepen value from each client. Based on these metrics, Guotai Haitong Securities expects the company to achieve full‑year profitability in 2026. Token‑Based Pricing: From Selling Tools to Value Sharing With the arrival of the token era, the role of tokens is undergoing a fundamental shift – they are no longer simply a unit of compute consumption but have become a direct carrier of business value. Xunce's core capability lies in providing vertical AI solutions that act as an "external brain" for general‑purpose large models, ensuring that every token consumed generates a measurable business return. Xunce's solutions are deeply embedded in clients' private clouds and on‑premises systems, acting as a "data hub." Token‑based pricing means the company's revenue is directly tied to clients' AI usage – the more clients use, the more the company earns. Building on this capability, the company is accelerating the evolution of its business model. The results announcement clearly states that Xunce is transitioning from project‑based and subscription models to token‑based pricing, evolving from a traditional tool provider into an "AI Agent enabler." According to the company, token‑based revenue accounted for 5% of total revenue in early 2026, and is expected to reach 20‑30% for the full year. From a financial perspective, this model unlocks three layers of value: first, revenue structure optimization, shifting from one‑time project delivery to recurring service revenue with significantly enhanced predictability; second, improved pricing power, as the company's revenue becomes tied to the value created for clients; and third, expanded profit margins, as project delivery becomes less dependent on headcount, creating room for margin expansion. NVIDIA's "Token Factory Economics" framework is validating this trend at the industry level: competition in the AI inference phase is shifting from "who has more compute" to "who can generate greater business value from each token." Xunce, with its deep expertise in processing high‑quality data across vertical industries, is perfectly positioned at this critical juncture. Strategic Depth: From Asset Management to Robotics and Commercial Aerospace Xunce started in the asset management industry – one of the most demanding sectors in terms of data real‑time requirements and regulatory compliance – where it holds the largest market share, covering the top 10 asset management institutions in China. It was precisely in this high‑concurrency, low‑latency, strong‑consistency environment that Xunce built its full‑stack AI Data Agent technology system, covering everything from data acquisition, cleaning, and standardization to real‑time computation and large model tuning, establishing a core technological moat in millisecond‑level real‑time data processing. In 2025, the company accelerated the replication of this capability across other industries, including telecommunications, power, energy, urban operations, high‑end manufacturing, and healthcare. The share of revenue from non‑asset management businesses increased further from 61.3% in 2024 to 79.6%, reflecting a more diversified business mix. By year‑end, the company had developed over 300 data modules, enabling rapid adaptation to different industry needs through modular combinations and significantly reducing the marginal cost of cross‑industry expansion. More forward‑looking is the company's expansion into two frontier areas: robotics data platforms and commercial aerospace. These scenarios, which demand extreme real‑time performance and reliability, serve both as a testing ground for technical capabilities and as an early entry into high‑growth future markets. In addition, the company plans to steadily advance its global expansion and actively establish strategic partnerships with leading domestic and international compute providers and algorithm companies, building an integrated ecosystem that coordinates compute, algorithms, and data. Valuation Undervaluation: Value Discovery for a Token Stock in Hong Kong In March 2026, Xunce Technology was officially included in the Hang Seng Composite Index. Once it becomes eligible for the Stock Connect program, liquidity is expected to improve significantly. Currently, the company's PS ratio is about 40x, as the token‑based business model accelerates, the company's valuation offers significant room for upside, with the potential to align with large model companies such as Minimax and Zhipu. Against the backdrop of the 15th Five‑Year Plan, which explicitly calls for "building a new form of intelligent economy" and deepening "AI+," demand for real‑time data infrastructure in the AI inference era is only just beginning. Xunce has demonstrated the explosive potential of growth through its revenue doubling, validated the sustainability of its model through its second‑half profitability, and opened up a new valuation narrative in the token economy through its upgrade to token‑based pricing. 27/03/2026 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.com
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Eisai and Nuvation Bio Announce Marketing Authorisation Application for Taletrectinib for the Treatment of Advanced ROS1-Positive Non-Small Cell Lung Cancer Validated by the European Medicines Agency JCN Newswire

Eisai and Nuvation Bio Announce Marketing Authorisation Application for Taletrectinib for the Treatment of Advanced ROS1-Positive Non-Small Cell Lung Cancer Validated by the European Medicines Agency

TOKYO and NEW YORK, NY., Mar 27, 2026 - (JCN Newswire) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”), a human-centered global leading research-based pharmaceutical company working in the neurology and oncology therapeutic areas, and Nuvation Bio Inc. (NYSE: NUVB, Corporate Headquarters: New York, NY, CEO: David Hung, M.D., “Nuvation Bio”), a global oncology company focused on tackling some of the toughest challenges in cancer treatment, today announced that the European Medicines Agency (EMA) has validated the Marketing Authorisation Application (MAA) for taletrectinib for the treatment of advanced ROS1-positive (ROS1+) non-small cell lung cancer (NSCLC). The filing will follow a standard review timeline.Taletrectinib (marketed as IBTROZI® in the U.S. and Japan) is a highly selective, next-generation oral treatment for patients living with advanced ROS1+ NSCLC.1 In January 2026, Eisai and Nuvation Bio announced they had entered into an exclusive licensing and collaboration agreement in Europe and additional countries* outside the U.S., China and Japan to extend the global reach of taletrectinib. Following this filing to the EMA, additional filings are planned for the U.K., Canada and other regions included in Eisai’s licensed territories.Across Europe, nearly 400,000 people are diagnosed with lung cancer each year with NSCLC accounting for 80% of cases.2,3 It is estimated that approximately 2% of patients with NSCLC have ROS1+ disease.4,5“The validation of the MAA is a significant moment for patients in Europe with ROS1+ NSCLC,” said Terushige Iike, Chief Business Officer of Eisai Co., Ltd. “With its efficacy and safety profile, we believe taletrectinib has the potential to become a standard of care therapy for the thousands of patients living with this aggressive disease in Europe. We look forward to working closely with the EMA during the review process with the goal of making this treatment available to appropriate patients who urgently need targeted options.”The application is based on data from the two pivotal Phase 2 clinical studies, TRUST-I and TRUST-II, evaluating taletrectinib in patients globally.6,7 Results from a pooled analysis of the TRUST clinical program were published in the Journal of Clinical Oncology in April 20258, and Nuvation Bio anticipates near-term disclosure of updated data reflecting even longer patient follow-up, further building on the depth and durability of responses observed to date. Additionally, given the comprehensive nature of the taletrectinib clinical dataset and based on favorable feedback received at a pre-submission meeting with the CHMP Rapporteur and Co-Rapporteur, the accepted MAA will be considered to support full approval.“Having seen the meaningful impact taletrectinib has already made for patients with ROS1+ NSCLC in the U.S., China and Japan, we are thrilled to partner with Eisai and have an accepted MAA for review in Europe,” said David Hung, M.D., Founder, President and Chief Executive Officer of Nuvation Bio. “This accepted filing represents an important milestone in our global development strategy and brings us one step closer to delivering this highly selective, next-generation oral therapy to more patients who need it in Europe and around the world.”In June 2025, the U.S. Food and Drug Administration (FDA) granted full approval to taletrectinib for the treatment of locally advanced or metastatic ROS1+ NSCLC across lines of therapy, following a Priority Review and double Breakthrough Therapy designations. Taletrectinib is also approved for patients with advanced ROS1+ NSCLC in Japan, where it is marketed by Nippon Kayaku, and in China, where it is marketed by Innovent Biologics under the brand name DOVBLERON®.* Eisai’s licensed territories: Europe, the Middle East, North Africa, Russia, Turkey, Canada, Australia, New Zealand, Singapore, the Philippines, Indonesia, Thailand, Malaysia, Vietnam and IndiaAbout ROS1+ NSCLCEach year, more than one million people globally are diagnosed with non-small cell lung cancer (NSCLC), the most common form of lung cancer.9 It is estimated that approximately 2% of patients with NSCLC have ROS1+ disease.4,5 About 35% of patients newly diagnosed with metastatic ROS1+ NSCLC have tumors that have spread to their brain.10 The brain is also the most common site of disease progression, with about 50% of previously treated patients developing central nervous system (CNS) metastases.10,11About TaletrectinibTaletrectinib is an oral, potent, CNS-active, selective, next-generation ROS1 inhibitor therapy. On June 11, 2025, following Priority Review and Breakthrough Therapy designations for both TKI-naive and TKI-pretreated disease, the U.S. Food and Drug Administration (FDA) approved taletrectinib for the treatment of adult patients with locally advanced or metastatic ROS1+ NSCLC. Learn more about taletrectinib in the U.S. at IBTROZI.com. 1About the TRUST Clinical ProgramThe TRUST clinical program comprises three registrational studies evaluating the safety and efficacy of taletrectinib. TRUST-I (NCT04395677) and TRUST-II (NCT04919811) are Phase 2 single-arm studies evaluating taletrectinib for the treatment of adults with advanced ROS1+ NSCLC in China (N=173) and globally (N=189), respectively. The primary endpoint of both studies is confirmed objective response rate (cORR) as assessed by an independent review committee. TRUST-IV (NCT07154706) is a Phase 3 placebo-controlled study evaluating taletrectinib for the adjuvant treatment of adults with resected early-stage ROS1+ NSCLC. The study will enroll approximately 180 patients in the U.S., Canada, Europe, Japan and China. The primary endpoint is disease-free survival as determined by investigator, and the primary completion date is estimated to be in 2030. Nuvation Bio is also sponsoring TRUST-III (NCT06564324), a confirmatory randomized Phase 3 study evaluating taletrectinib versus crizotinib in 138 patients in China with advanced ROS1+ NSCLC who have not previously received ROS1 TKIs.6,7About Eisai Co., Ltd.Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." Under this Concept (also known as human health care (hhc) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various activities together with global partners.For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai Co., Ltd.), and connect with us on X, LinkedIn and Facebook. The website and social media channels are intended for audiences outside of the UK and Europe.About Nuvation BioNuvation Bio is a global oncology company focused on tackling some of the toughest challenges in cancer treatment with the goal of developing therapies that create a profound, positive impact on patients’ lives. Our diverse pipeline includes taletrectinib (IBTROZI®), a next-generation ROS1 inhibitor; safusidenib, a brain-penetrant IDH1 inhibitor; and an innovative drug-drug conjugate (DDC) program.Nuvation Bio was founded in 2018 by biopharma industry veteran David Hung, M.D., who previously founded Medivation, Inc., which brought to patients one of the world’s leading prostate cancer medicines. Nuvation Bio has offices in New York, San Francisco, Boston, and Shanghai. For more information, visit www.nuvationbio.com or follow the company on LinkedIn and X (@nuvationbioinc).U.S. IndicationIBTROZI is indicated for the treatment of adult patients with locally advanced or metastatic ROS1+ nonsmall cell lung cancer (NSCLC).IMPORTANT SAFETY INFORMATION FOR IBTROZI® (taletrectinib)1WARNINGS AND PRECAUTIONSHepatotoxicity: Hepatotoxicity, including drug-induced liver injury and fatal adverse reactions, can occur. 88% of patients experienced increased AST, including 10% Grade 3/4. 85% of patients experienced increased ALT, including 13% Grade 3/4. Fatal liver events occurred in 0.6% of patients. Median time to first onset of AST or ALT elevation was 15 days (range: 3 days to 20.8 months).Increased AST or ALT each led to dose interruption in 7% of patients and dose reduction in 5% and 9% of patients, respectively. Permanent discontinuation was caused by increased AST, ALT, or bilirubin each in 0.3% and by hepatotoxicity in 0.6% of patients.Concurrent elevations in AST or ALT ≥3 times the ULN and total bilirubin ≥2 times the ULN, with normal alkaline phosphatase, occurred in 0.6% of patients.Interstitial Lung Disease (ILD)/Pneumonitis: Severe, life-threatening, or fatal ILD or pneumonitis can occur. ILD/pneumonitis occurred in 2.3% of patients, including 1.1% Grade 3/4. One fatal ILD case occurred at the 400 mg daily dose. Median time to first onset of ILD/pneumonitis was 3.8 months (range: 12 days to 11.8 months).ILD/pneumonitis led to dose interruption in 1.1% of patients, dose reduction in 0.6% of patients, and permanent discontinuation in 0.6% of patients.QTc Interval Prolongation: QTc interval prolongation can occur, which can increase the risk for ventricular tachyarrhythmias (e.g., torsades de pointes) or sudden death. IBTROZI prolongs the QTc interval in a concentration-dependent manner.In patients who received IBTROZI and underwent at least one post baseline ECG, QTcF increase of >60 msec compared to baseline and QTcF >500 msec occurred in 13% and 2.6% of patients, respectively. 3.4% of patients experienced Grade ≥3. Median time from first dose of IBTROZI to onset of ECG QT prolongation was 22 days (range: 1 day to 38.7 months). Dose interruption and dose reduction each occurred in 2.8% of patients.Significant QTc interval prolongation may occur when IBTROZI is taken with food, strong and moderate CYP3A inhibitors, and/or drugs with a known potential to prolong QTc. Administer IBTROZI on an empty stomach. Avoid concomitant use with strong and moderate CYP3A inhibitors and/or drugs with a known potential to prolong QTc.Hyperuricemia: Hyperuricemia can occur and was reported in 14% of patients, with 16% of these requiring urate-lowering medication without pre-existing gout or hyperuricemia. 0.3% of patients experienced Grade ≥3. Median time to first onset was 2.1 months (range: 7 days to 35.8 months). Dose interruption occurred in 0.3% of patients.Myalgia with Creatine Phosphokinase (CPK) Elevation: Myalgia with or without CPK elevation can occur. Myalgia occurred in 10% of patients. Median time to first onset was 11 days (range: 2 days to 10 months).Concurrent myalgia with increased CPK within a 7-day time period occurred in 0.9% of patients. Dose interruption occurred in 0.3% of patients with myalgia and concurrent CPK elevation.Skeletal Fractures: IBTROZI can increase the risk of fractures. ROS1 inhibitors as a class have been associated with skeletal fractures. 3.4% of patients experienced fractures, including 1.4% Grade 3. Some fractures occurred in the setting of a fall or other predisposing factors. Median time to first onset of fracture was 10.7 months (range: 26 days to 29.1 months). Dose interruption occurred in 0.3% of patients.Embryo-Fetal Toxicity: Based on literature, animal studies, and its mechanism of action, IBTROZI can cause fetal harm when administered to a pregnant woman.ADVERSE REACTIONSAmong patients who received IBTROZI, the most frequently reported adverse reactions (≥20%) were diarrhea (64%), nausea (47%), vomiting (43%), dizziness (22%), rash (22%), constipation (21%), and fatigue (20%).The most frequently reported Grade 3/4 laboratory abnormalities (≥5%) were increased ALT (13%), increased AST (10%), decreased neutrophils (5%), and increased creatine phosphokinase (5%).DRUG INTERACTIONSStrong and Moderate CYP3A Inhibitors/CYP3A Inducers and Drugs that Prolong the QTc Interval: Avoid concomitant use.Gastric Acid Reducing Agents: Avoid concomitant use with PPIs and H2 receptor antagonists. If an acid-reducing agent cannot be avoided, administer locally acting antacids at least 2 hours before or 2 hours after taking IBTROZI. OTHER CONSIDERATIONSPregnancy: Please see important information in Warnings and Precautions under Embryo-Fetal Toxicity.Lactation: Advise women not to breastfeed during treatment and for 3 weeks after the last dose.Effect on Fertility: Based on findings in animals, IBTROZI may impair fertility in males and females. The effects on animal fertility were reversible.Pediatric Use: The safety and effectiveness of IBTROZI in pediatric patients has not been established.Photosensitivity: IBTROZI can cause photosensitivity. Advise patients to minimize sun exposure and to use sun protection, including broad-spectrum sunscreen, during treatment and for at least 5 days after discontinuation. Please see accompanying full U.S. Prescribing Information.(1) Nuvation Bio Inc. IBTROZI (taletrectinib) US prescribing information. Available at: https://ibtrozipi.com/IBTROZI_taletrectinib-prescribing-information.pdf. Last accessed: March 2026(2) Wood R, Taylor-Stokes G. Cost burden associated with advanced non-small cell lung cancer in Europe and influence of disease stage. Available here. Last accessed: March 2026(3) European Lung Foundation. Lung cancer. Available here. Last accessed: March 2026(4) Patil T, Smith DE, Bunn PA Jr, et al. The incidence of brain metastases in stage IV ROS1-rearranged non-small cell lung cancer and rate of central nervous system progression on crizotinib. J Thorac Oncol. 2018;13(11):1717-1726. doi:10.1016/j.jtho.2018.07.012.(5) Drilon A, Camidge DR, Lin JJ, et al. Repotrectinib in ROS1 fusion-positive non-small-cell lung cancer. N Engl J Med. 2024;390(2):118-131. doi:10.1056/NEJMoa2302299. (6) ClinicalTrials.gov. A Study of AB-106 in Advanced NSCLC With ROS1 Fusion (NCT04395677). Available at: https://clinicaltrials.gov/study/NCT04395677 . Last accessed: March 2026(7) ClinicalTrials.gov. A single-arm Phase 2 study of taletrectinib in advanced ROS1-positive NSCLC (NCT04919811). Available at: https://clinicaltrials.gov/study/NCT04919811 . Last accessed: March 2026(8) Pérol M, A., et al. Taletrectinib in ROS1-positive non-small cell lung cancer: TRUST. Journal of Clinical Oncology, 43(16), 1920–1929. https://doi.org/10.1200/JCO-25-00275(9) Global Data. Diagnosed incident cases of non-small cell lung cancer across 8MM to reach 1.46 million in 2032, forecasts GlobalData. Available here. Last accessed: March 2026(10) Patil T, Smith DE, Bunn PA Jr, et al. The incidence of brain metastases in stage IV ROS1-rearranged non-small cell lung cancer and rate of central nervous system progression on crizotinib. J Thorac Oncol. 2018;13(11):1717-1726. doi:10.1016/j.jtho.2018.07.012.(11) Drilon A, Camidge DR, Lin JJ, et al. Repotrectinib in ROS1 fusion-positive non-small-cell lung cancer. N Engl J Med. 2024;390(2):118-131.MEDIA CONTACTSEisai Co., Ltd.Public Relations DepartmentTEL: +81 (0)3-3817-5120Nuvation Bio Inc.Kaitlyn Nealymedia@nuvationbio.comINVESTOR CONTACTSEisai Co., Ltd.Investor Relations DepartmentTEL: +81 (0) 3-3817-5122Nuvation Bio Inc.JR DeVitair@nuvationbio.comForward-Looking Statements of Nuvation Bio Inc.Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding taletrectinib’s therapeutic potential and the urgent need for new therapeutic options for patients with advanced ROS1+ NSCLC in Europe, our expectations that the MAA filing for taletrectinib will follow a standard review with a decision in 1H 2027 and be considered for full approval, plans for additional filings for the U.K., Canada and other regions included in Eisai’s licensed territories, and expectations for near-term disclosure of updated data. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the management team of Nuvation Bio and are not predictions of actual performance. These forward-looking statements are subject to a number of risks and uncertainties that may cause actual results to differ from those anticipated by the forward-looking statements, including but not limited to the challenges associated with conducting drug discovery and commercialization, and initiating or conducting clinical studies due to, among other things, difficulties or delays in the regulatory process, enrolling subjects or manufacturing or acquiring necessary products; the emergence or worsening of adverse events or other undesirable side effects; risks associated with preliminary and interim data, which may not be representative of more mature data; physician and patient behavior; and competitive developments. Risks and uncertainties facing Nuvation Bio are described more fully in its Form 10-K filed with the SEC on March 2, 2026 under the heading “Risk Factors,” and other documents that Nuvation Bio has filed or will file with the SEC. You are cautioned not to place undue reliance on the forward-looking statements, which speak only as of the date of this press release. Nuvation Bio disclaims any obligation or undertaking to update, supplement or revise any forward-looking statements contained in this press release. Copyright 2026 JCN Newswire. All rights reserved. www.jcnnewswire.com
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EveryMatrix memperluas platform agregasi melalui kemitraan dengan Eeze

(AsiaGameHub) - EveryMatrix telah berhasil meningkatkan platform agregasinya melalui kemitraan dengan Eeze, yang memungkinkan para mitranya di seluruh dunia untuk mendapatkan akses ke portofolio konten live dealer dan RNG milik Eeze. Dua konten baru terbesar di platform EveryMatrix mencakup Fusion Roulette yang baru saja diluncurkan dan permainan slot pertama dari Eeze. Bjorn Sjoberg, Chief Commercial Officer di EveryMatrix, mengatakan: Kami sangat senang dapat menambahkan rangkaian produk lengkap Eeze ke dalam penawaran agregasi kami. Dengan produk live terbaik di kelasnya dan deretan permainan RNG yang menarik dalam rencana pengembangan kami, kami yakin bahwa pelanggan kami akan menikmati diferensiasi yang dibawa oleh judul-judul ini ke pasar. Mikko Hoglund, Partnership Manager di Eeze, menambahkan: Bermitra dengan EveryMatrix merupakan momen penting bagi kami saat kami berupaya untuk mendorong permainan kami ke jaringan pemain yang lebih luas dari sebelumnya. Kami memiliki banyak rilis produk menarik yang akan hadir dalam beberapa bulan ke depan, dan kami tahu bahwa permainan ini, serta portofolio kami yang sudah ada, akan diterima dengan baik di seluruh basis pelanggan EveryMatrix. Senada dengan hal tersebut, EveryMatrix telah memperluas kehadirannya di pasar AS. Bulan lalu mereka bekerja sama dengan Ocean Casino Resort di New Jersey, menyediakan berbagai pilihan lebih dari 45.000 judul dari lebih dari 360 pemasok bagi para pemain platform online Ocean Resort, betOcean, melalui platform kasino EveryMatrix. Dengan demikian, ini merupakan kemitraan kelima bagi EveryMatrix di Amerika Utara dan ketiga di Amerika Serikat. Perusahaan tersebut kini memegang lisensi di Connecticut, Michigan, New Jersey, Pennsylvania, dan West Virginia serta di Ontario, Kanada. Di antara rekanannya adalah bet365, BetPark Delaware North, dan Pinnacle. Mark Burroughes, Chief Commercial Officer of Casino di EveryMatrix, mengatakan pada saat itu: Bermitra dengan betOcean adalah langkah krusial dalam strategi pertumbuhan kami. Menyelesaikan integrasi agregasi penuh dalam waktu kurang dari empat bulan, termasuk persetujuan regulasi, menunjukkan pengalaman mendalam kami dalam menghadirkan konten yang patuh di AS. Artikel ini disediakan oleh penyedia konten pihak ketiga. AsiaGameHub (https://asiagamehub.com/) tidak memberikan jaminan atau pernyataan apa pun terkait isinya. Kategori: Berita Terkini, Pembaruan Umum AsiaGameHub menyediakan layanan distribusi iGaming yang ditargetkan untuk perusahaan dan organisasi, dengan menghubungkan lebih dari 3.000 media premium di Asia dan lebih dari 80.000 influencer spesialis. Platform ini menjadi jembatan utama untuk distribusi konten iGaming, kasino, dan eSports di seluruh kawasan ASEAN.
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17.000 orang bergabung dalam gugatan kelas terhadap kesalahan Togel Norsk Tipping iGame

17.000 orang bergabung dalam gugatan kelas terhadap kesalahan Togel Norsk Tipping

(AsiaGameHub) - Gugatan class action terhadap Norsk Tipping telah menarik lebih dari 17.000 penggugat, menjadikannya gugatan class action terbesar dalam sejarah Norwegia. Gugatan ini diprakarsai oleh firma hukum SANDS setelah kesalahan dalam sistem lotre dan pengundian Lotto serta Eurojackpot dikonfirmasi telah memengaruhi peluang kemenangan bagi para pemain. Batas waktu untuk bergabung dalam gugatan ini adalah 16 Februari 2026. Menurut otoritas perjudian Norwegia, kesalahan-kesalahan ini memengaruhi beberapa undian yang dilakukan selama beberapa tahun. Mitra SANDS, Lars Tormodsgard, meyakini bahwa kesalahan-kesalahan tersebut mengakibatkan pemain menerima peluang yang lebih rendah dari yang diiklankan, yang merupakan cacat mendasar dalam pengoperasian permainan-permainan tersebut. Para penggugat menuntut pengembalian dana untuk semua aktivitas taruhan mereka yang terjadi sebelum identifikasi masalah. Taruhan selama periode yang memengaruhi penggugat dari 2015/2016 hingga 2025 bervariasi secara luas dari jumlah yang sangat kecil hingga jumlah yang besar. Nilai total kasus ini belum ditetapkan; namun, dengan begitu banyak penggugat, nilainya bisa sangat besar. Norsk Tipping telah mengakui sifat teknis dari kesalahan-kesalahan tersebut tetapi menyangkal tanggung jawab. Meskipun operator mengakui kesalahan-kesalahan tersebut memang terjadi; mereka berpendapat bahwa kesalahan-kesalahan tersebut hanya memengaruhi undian tambahan dari permainan dan tidak menjamin pengembalian semua taruhan pada semua undian. Operator telah menyatakan bahwa mereka akan membela diri di pengadilan. Norsk Tipping terlibat dalam gugatan lain, di samping berbagai tantangan regulasi lainnya selama beberapa tahun terakhir yang juga mengakibatkan dikenakannya berbagai sanksi dengan total NOK 119 juta (sekitar $14 juta) atas berbagai kegagalan teknis/operasional; termasuk denda NOK 46 juta karena kesalahan yang terjadi selama undian. Menurut pihak berwenang, kesalahan khusus ini berpotensi telah ada selama 10 tahun yang mungkin telah memberikan keuntungan signifikan bagi pemain sindikat dibandingkan pemain individu. Persidangan dijadwalkan akan dimulai pada tanggal 25–26 Agustus 2016; dan tergantung pada hasilnya tidak hanya akan memiliki dampak finansial yang besar bagi Norsk Tipping, tetapi juga dapat menetapkan preseden penting terkait bagaimana kesalahan terkait perjudian ditangani di pasar yang diatur. Artikel ini disediakan oleh penyedia konten pihak ketiga. AsiaGameHub (https://asiagamehub.com/) tidak memberikan jaminan atau pernyataan apa pun terkait isinya. Kategori: Berita Terkini, Pembaruan Umum AsiaGameHub menyediakan layanan distribusi iGaming yang ditargetkan untuk perusahaan dan organisasi, dengan menghubungkan lebih dari 3.000 media premium di Asia dan lebih dari 80.000 influencer spesialis. Platform ini menjadi jembatan utama untuk distribusi konten iGaming, kasino, dan eSports di seluruh kawasan ASEAN.
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Amap Street Stars Launches Macao Authentic Delicacies Ranking to Drive Cultural-Tourism Innovation in the Greater Bay Area

EQS Newswire / 27/03/2026 / 16:02 UTC+8 Sands China, Amap and Macau Pass Sign Strategic Cooperation Memorandum to inject new vitality into Macao’s development as a City of Gastronomy (27 March 2026, Macao) Amap and Macau Pass held the “Macao City Life Launch Event” at The Londoner® Macao on March 27. The event was co-organized by Sands China Ltd. and supported by the Macao Government Tourism Office. Meanwhile, Amap, Macau Pass, and Sands China held a signing ceremony for a tripartite strategic cooperation memorandum. At the event, Amap unveiled the world’s first citywide “Flying Street View” and, together with Macau Pass, launched the “Macao Authentic Delicacies” Ranking and the “Macao City Life Support Program”. These initiatives aim to leverage AI and digital technologies to deepen the integration of culture and tourism across the Guangdong-Hong Kong-Macao Greater Bay Area, setting a new benchmark for high-quality development in the regional service sector. Maria Helena de Senna Fernandes, Director of the Macao Government Tourism Office, said Macao is stepping up efforts to integrate tourism and gastronomy, making the debut of Amap Street Stars in the city—its first stop in the Greater Bay Area—particularly meaningful. “The newly launched ‘Macao Authentic Delicacies’ Ranking will help visitors discover distinctive local businesses with greater precision and further unlock tourism spending,” she said. “Macao will continue working with all sectors to advance the high-quality development of its tourism industry.” Photo caption: “Macao City Life Support Program” Officially Launched Real Data Builds Trust, Helping Visitors Discover Macao Through Food Macao recorded over 40 million visitor arrivals in 2025, reaching a new high. To help travelers better explore the city through its culinary offerings, Amap and Macau Pass introduced the “Macao Authentic Delicacies” Ranking, covering six categories: popular dim sum restaurants, specialty dessert shops, wok-hei eateries, street-side noodle shops, local milk tea and coffee spots, and neighborhood cha chaan tengs—offering a comprehensive view of Macao’s diverse food scene. Unlike conventional rankings that rely on subjective reviews or commercial promotion, Amap Street Stars operates on a “vote with their feet” mechanism, drawing on large volumes of real navigation and in-store visit data to create a credible, data-driven evaluation system for offline services. This approach captures the essence of Macao as a "City of Gastronomy," helping visitors discover the distinctive flavors hidden in the alleyways and rich with local spirit—so travelers can truly taste authentic Macao in every choice they make. In Macao, the rankings currently cover 985 merchants, with 96 restaurants, attractions, and hotels selected for the top-tier “Champion List.” The rankings are also integrated with major attractions and curated “Citywalk” routes via a newly launched “Explore Macao with Amap Street Stars” page—creating a seamless, one-stop experience that connects discovery, decision-making, navigation, and in-store visits. World’s First Citywide “Flying Street View”: Technology Enhances the Cultural Tourism Experience Another highlight of the event was the launch of Amap’s citywide “Flying Street View” in Macao, powered by its self-developed world model. This feature allows users to explore 360-degree aerial views of the city and preview landmarks such as the Ruins of St. Paul’s and St. Dominic’s Church, while virtually navigating neighborhoods to experience local shops and street life. It is designed to simplify trip planning and significantly reduce the time and effort required to decide where to go. The feature also provides merchants with a powerful new way to showcase their businesses, helping improve customer conversion. Pastelaria Yeng Kee, a heritage brand with a 98-year history, reported a 23% increase in average daily sales at its Rua das Estalagens location after adopting the feature. Similarly, local brand Matcha Macau leveraged Amap’s digital location tools and in-store reservation features to address map positioning inaccuracies and customer loss caused by overlapping street names, successfully attracting more visitors from the Chinese mainland. “Macao City Life Support Program” Aims to Help Quality Merchants Get Seen Since the launch of Amap Street Stars in September 2025, the platform has driven over 380 million visits to restaurants, attractions, and hotels across the Greater Bay Area’s 11 cities. During the 2026 Chinese New Year holiday, Macao welcomed an average of 114,000 daily visitors from the Chinese mainland, with Zhuhai, Guangzhou, and Shenzhen contributing the largest shares—highlighting the impact of the Greater Bay Area’s “one-hour living circle” on Macao’s tourism growth. To help merchants capture this growing demand, Amap and Macau Pass jointly launched the “Macao City Life Support Program,” focusing on well-known brands, heritage shops, and quality neighborhood businesses. The program provides support through four key initiatives: First, it builds “AI-powered digital storefronts”, using Flying Street View and AI service tools to help merchants improve efficiency and increase revenue. Second, it provides operational tools and professional offline training to enhance digital capabilities. Third, it invests millions in consumer vouchers and delivers tens of millions of traffic exposure to help merchants turn traffic advantage into order growth during peak travel seasons. Fourth, it collaborates with Amap’s “Authentic Explorer” influencers to create high-quality content and amplify brand visibility. Amap and Macau Pass Join Forces with Sands China to Boost Macao's Cultural-Tourism Industry with Digital Technology At the event, Amap, Macau Pass, and Sands China signed a strategic cooperation memorandum to further bolster the digital transformation of Macao’s cultural tourism industry. As a leading integrated resort operator in Macao, Sands China integrates its newly launched Sands Lifestyle membership platform into Amap’s digital ecosystem. The partnership will focus on brand marketing, smart navigation, and the digital upgrade of commercial districts. Sands China has long placed strong emphasis on the development of its F&B segment, with over 150 restaurants that range from fine dining to regional specialties. Looking ahead, Sands China will further integrate with Amap’s digital ecosystem to create a seamless, one-stop smart experience—from precise online outreach to immersive offline experiences. Dr. Wilfred Wong, Executive Vice Chairman of Sands China Ltd., said: " We are honored to be the first integrated resort operator in Macao to establish such a deep partnership with Amap. This partnership marks an important step toward empowering our dining offerings with digital technology and support the broader development of Macao’s culinary industry. Sands China will continue to deepen its digital practices, enabling visitors to explore the culinary delights of Sands China and Macao through smart technology, while injecting new momentum into Macao’s development as a Creative City of Gastronomy." Guo Ning, CEO of Amap, said “Street Stars was created to build a trusted offline service ecosystem based on real consumer choices. By enabling users to ‘vote with their feet,’ we aim to ensure that quality businesses receive the recognition they deserve. Meanwhile, this partnership marks the deep integration of Amap’s digital capabilities with Macao’s cultural tourism industry. In the future, we plan to expand cooperation into more areas and look forward to working with our partners to transform Macao’s unique appeal into measurable and shareable trust assets, setting a new model for tourism innovation across the Greater Bay Area.” As a key driver of Macao’s digital transformation, Macau Pass is leveraging over 20 years of experience in local consumer services together with Amap’s AI-powered mobility solutions. The collaboration makes it easier for visitors to discover specialty merchants on digital maps while streamlining payments to enhance customer conversion. Sun Ho, Chairman and CEO of Macau Pass, stated that the partnership with Amap and Sands China aims to harness digital technology to support local businesses, showcase Macao’s unique charm to more visitors, and invigorate the city’s economic vitality. Photo caption: Signing Ceremony of the Tripartite Strategic Cooperation Memorandum between Guo Ning, CEO of Amap; Dr. Wilfred Wong, Executive Vice Chairman of Sands China Ltd.; and Sun Ho, Chairman and CEO of Macau Pass. ### About Sands China Ltd. Sands China is the largest operator of integrated resorts in Macao. The Company’s integrated resorts on the Cotai Strip comprise The Venetian® Macao, The Plaza® Macao, The Parisian® Macao and The Londoner® Macao. The Company also owns and operates Sands® Macao on the Macao peninsula. The Company’s portfolio features a diversified mix of leisure and business attractions and transportation operations, including large meeting and convention facilities; a wide range of restaurants; shopping malls; world-class entertainment at The Venetian Arena, The Londoner Arena, The Venetian Theatre, The Parisian Theatre, the Londoner Theatre and the Sands Theatre; and a high-speed Cotai Water Jet ferry service between Hong Kong and Macao. The Company’s Cotai Strip portfolio has the goal of contributing to Macao’s transformation into a world centre of tourism and leisure. For more information, please visit www.sandschina.com. About Amap China's leading provider of digital map, navigation, real-time traffic information and lifestyle services Founded in 2002, Amap is a leading provider of digital map, navigation, real-time traffic information and lifestyle services in China. With a focus on "promoting technological innovation and advancing with the ecosystem," Amap has evolved into an integrated one-stop travel and lifestyle service platform. The platform provides various transportation services covering driving, ride-hailing, buses, subways, cycling, walking, trains, and flights, as well as quality lifestyle services including dining, hotel & travel, and gas/charging. Amap is dedicated to building a new offline service credit system based on users voting with their feet. Amap will continue to develop public welfare initiatives such as barrier-free transportation and eco-friendly transportation, which have received positive recognition from the industry and users. About Macau Pass Group Holdings Limited Macau Pass Group Holdings Limited is a diversified group company engaged in various fields, including financial technology, payment services, local lifestyle services, tourism services, and cultural performances. Macau Pass Group is committed to continuous innovation and development, aiming to serve as a bridge connecting Macao with the world and promoting the common prosperity of the regional economy and culture. One of subsidiaries of Macau Pass Group, Macau Pass S.A, has issued the first contactless smart electronic payment card in Macao, the mCard, with a cumulative issuance exceeding five million cards, meeting the payment needs of all residents and tourists at nearly 30,000 payment points in Macao. Its sub-brand, MPay, registered users accounting for over 90% of the total local population and is also the local app with the highest daily active users in Macao. Macau Pass Group also operates a highly recognized and utilized membership points system in Macao, mCoin, which has partnered with various cultural, sports, and exhibition events. mPass integrates a variety of one-stop local services, providing consumers visiting Macao with a diverse range of products and services, including dining, cultural entertainment, transportation, shopping, and travel vacations, taking consumers to explore the vibrant life in Macao. Media contacts: Public Relations, Sands China Ltd. Dan Li Tel: +853 8118 2056 Email: dan.li@sands.com.mo Public Relations, Amap Song Guangping Email: songguangping.sgp@alibaba-inc.com Public Relations, Macau Pass Group Holdings Ltd. May Email: myt455242@alibaba-inc.com 27/03/2026 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.com
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Melinda French Gates memiliki aturan untuk konflik di tempat kerja: Tunggu 48 jam sebelum mengatakan apapun

(SeaPRwire) - Melinda French Gates telah membagikan rumus rahasianya untuk menangani konflik di tempat kerja. Dia menunda itu. “Jika saya tidak senang dengan pekerjaan yang Anda lakukan, Anda akan mendengar dari saya dalam 48 jam,” kata French Gates kepada podcast Bloomberg Business‘s Leaders with Francine Lacqua minggu ini. “Saya tidak akan memberitahu Anda segera, karena saya membutuhkan waktu untuk memikirkannya.” “Jika saya marah tentang sesuatu [saya lakukan ini] untuk tenang,” tambahnya. “Itu tanggung jawab saya.” Praktik ini, jelasnya, kurang tentang menahan kritik dan lebih tentang menyampaikannya dengan jujur, integritas, dan kemurahan hati. Sisi lain dari jam 48-jam juga sama disengaja. Jika jendela tertutup tanpa umpan balik apapun, itu berarti karyawan aman. “Jika mereka melewati batas 48 jam, mereka dapat yakin bahwa pekerjaan yang mereka lakukan adalah pekerjaan yang bagus,” katanya. “Anda tidak akan sampai ke tinjauan kinerja dan mendapat kejutan.” Ini adalah praktik yang telah ditingkatkan oleh filantropis miliarder ini selama beberapa dekade. Dia menjabat sebagai ketua bersama Bill & Melinda Gates Foundation, organisasi amal swasta terbesar di dunia, dari tahun 2000 hingga dia mengundurkan diri pada tahun 2024, sekitar tiga tahun setelah perceraian pasangan itu. Saat ini, French Gates menjalankan organisasinya sendiri, Pivotal Ventures, sebuah perusahaan investasi dan inkubasi yang dia dirikan pada tahun 2015 untuk memajukan peluang bagi perempuan dan keluarga di AS. Sebagai bagian dari kesepakatan perceraiannya dengan pendiri Microsoft, French Gates menerima $12,5 miliar untuk diarahkan ke pekerjaan filantropi melalui Pivotal. Dia berkomitmen menambahkan $1 miliar setiap tahun hingga 2026 untuk memajukan kekuatan perempuan secara global. Pendekatan Melinda French Gates terhadap kepemimpinan dan bagaimana ia dibandingkan dengan eksekutif lain Lacqua dari Bloomberg menyajikan pendekatan French Gates terhadap umpan balik sebagai “kekuatan super kepemimpinan”nya, yang membutuhkan disiplin emosional dan kejujuran. “Menjadi jelas adalah kebaikan,” jawab French Gates, “karena saya memberinya umpan balik sehingga mereka benar-benar dapat berkembang dan menjadi lebih baik.” French Gates juga menggambarkan mantra umpan balik 48-jamnya sebagai mempertahankan integritas pribadi sambil menjaga martabat orang lain tetap utuh: “ramah, bijaksana, sebelum Anda masuk ke dalamnya.” Filsafatnya bertentangan dengan beberapa budaya umpan balik yang lebih agresif dari eksekutif lain. Ray Dalio, misalnya, membangun budaya perusahaannya di sekitar apa yang dia sebut “radical transparency” (transparansi radikal), sebuah sistem di mana karyawan di setiap level diharapkan untuk memberikan kritik real-time tanpa filter, dan hampir setiap rapat direkam untuk analisis post-mortem. “Jika Anda mulai menyadari, secara intelektual, bahwa menjadi sangat jujur satu sama lain adalah sesuatu yang harus dihargai,” kata Dalio kepada Business Insider. “Ini akan membangun kepercayaan.” “Ada banyak kepercayaan yang berlangsung,” tambah Dalio, yang mendirikan Bridgewater Associates, perusahaan hedge fund terbesar di dunia. Dia bahkan mengingat kepada Business Insider saat seorang staf junior mengirimkannya email memberikan nilai kinerjanya dalam rapat sebagai “D-” karena tidak teratur. Jadi sementara Dalio lebih suka ketepatan waktu dan umpan balik mentah, French Gates memilih waktu refleksi lebih banyak dan nada yang hormat. CEO Microsoft Satya Nadella mengambil pendekatan yang sedikit berbeda. Ketika dia menjabat kepala Microsoft, dia mendorong untuk mengubah budaya “know-it-all” (tau-semua) menjadi budaya “learn-it-all” (pelajari-semua)—yang berlandaskan kerendahan hati, rasa ingin tahu, dan keamanan psikologis. Ini adalah mantra yang terinspirasi oleh psikolog Amerika Carol Dweck, yang paling terkenal karena penelitiannya tentang motivasi dan pola pikir. “Jika Anda mengambil dua orang, satu di antaranya adalah learn-it-all dan yang lain adalah know-it-all, learn-it-all akan selalu mengalahkan know-it-all dalam jangka panjang, bahkan jika mereka mulai dengan kemampuan bawaan yang lebih sedikit,” kata Nadella kepada Bloomberg dalam wawancara 2016. Namun, French Gates jelas tidak menghindari percakapan sulit. “Saya tidak keberatan dengan konflik,” katanya kepada Bloomberg. “Saya belajar untuk melakukannya dengan cara yang mempertahankan integritas saya.” Artikel ini disediakan oleh penyedia konten pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberikan jaminan atau pernyataan sehubungan dengan hal tersebut. Sektor: Top Story, Daily News SeaPRwire menyediakan distribusi siaran pers real-time untuk perusahaan dan lembaga, menjangkau lebih dari 6.500 toko media, 86.000 editor dan jurnalis, dan 3,5 juta desktop profesional di 90 negara. SeaPRwire mendukung distribusi siaran pers dalam bahasa Inggris, Korea, Jepang, Arab, Cina Sederhana, Cina Tradisional, Vietnam, Thailand, Indonesia, Melayu, Jerman, Rusia, Prancis, Spanyol, Portugis dan bahasa lainnya.
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Bede Gaming menerima lisensi pemasok satu tahun dari AGLC menjelang peluncuran iGaming Alberta

(AsiaGameHub) - Bede Gaming telah mendapatkan persetujuan sementara dari dewan Alberta Gaming, Liquor and Cannabis (AGLC) untuk lisensi supplier satu tahun. Lisensi ini memungkinkan perusahaan untuk menjadi salah satu pemain terkemuka di pasar perjudian online yang sepenuhnya diatur di Alberta, yang diharapkan diluncurkan akhir tahun ini. Lisensi ini, yang untuk Pemasok Barang atau Jasa iGaming, memberdayakan Bede Gaming—yang merupakan bagian dari Merkur Group Jerman—untuk menawarkan platform dan layanannya kepada operator yang sedang menyiapkan peluncuran pasar iGaming Alberta. Dengan memperoleh status sebagai salah satu supplier berlisensi paling awal di provinsi tersebut, Bede Gaming akan berada dalam posisi untuk memanfaatkan peluang bisnis pertama dari pembukaan pasar Alberta. Tumpukan teknologinya (technology stack) telah bersertifikat SOC 2 dan terdiri dari perangkat lunak sendiri ditambah lebih dari 150 integrasi pihak ketiga. Melalui ini, perusahaan ingin memudahkan mitra untuk memasuki pasar dan sekaligus mendukung pertumbuhan jangka panjang mereka. Meskipun provinsi tersebut baru mulai mendaftarkan operator pada Januari 2026, beberapa ahli industri berpikir bahwa pertumbuhan utama pasar ini bisa mirip dengan sektor iGaming Ontario. Selain itu, provinsi tersebut sedang menjadi pusat populer yang dikenal luas untuk operator internasional yang memasuki Amerika Utara. Colin Cole-Johnson, Chief Executive Officer di Bede Gaming, mengatakan: Bede senang menerima persetujuan peraturan bersyarat untuk bekerja di Alberta, yang menempatkan kami pada posisi yang kuat untuk mendukung operator dengan ekspansi mendatang mereka di provinsi ini. Kami memiliki investasi jangka panjang di industri iGaming Kanada, dan saya sangat antusias untuk peluang seru yang akan datang di pasar baru ini. Sebagai salah satu pelamar pertama yang diakui secara resmi oleh regulator, Bede menawarkan layanan yang benar-benar dilokalkan kepada mitranya—and fakta bahwa mereka bersertifikat SOC 2 akan memungkinkan mitra untuk segera beroperasi begitu saja mereka siap meluncurkan. Artikel ini disediakan oleh penyedia konten pihak ketiga. AsiaGameHub (https://asiagamehub.com/) tidak memberikan jaminan atau pernyataan apa pun terkait isinya. Kategori: Berita Terkini, Pembaruan Umum AsiaGameHub menyediakan layanan distribusi iGaming yang ditargetkan untuk perusahaan dan organisasi, dengan menghubungkan lebih dari 3.000 media premium di Asia dan lebih dari 80.000 influencer spesialis. Platform ini menjadi jembatan utama untuk distribusi konten iGaming, kasino, dan eSports di seluruh kawasan ASEAN.
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New “L00 Series” Train for the Seibu Railway’s Yamaguchi Line Begins Commercial Operation JCN Newswire

New “L00 Series” Train for the Seibu Railway’s Yamaguchi Line Begins Commercial Operation

The Frst New Leo Liner "L00 Series"TOKYO, Mar 27, 2026 - (JCN Newswire) - Mitsubishi Heavy Industries, Ltd. (MHI) has completed delivery of the first trainsets L00 Series ("Leo-kei") trains (4 cars per trainset, total 12 cars) ordered by Seibu Railway Co., Ltd. for its Yamaguchi Line, an automated guideway transit (AGT) system. Commercial operation of the first train began on March 27th. That same day, Seibu Railway held a commemorative ceremony for the start of commercial operation, attended by Tokorozawa City Mayor Masatoshi Onozuka and Higashimurayama City Mayor Takashi Watanabe.The new L00 Series are being manufactured at MHI's Mihara Machinery Works in Hiroshima Prefecture, and are scheduled to be delivered sequentially by FY2027. The seating arrangement has been changed from the bench seats used in the existing 8500 Series vehicles to longitudinal seats to increase transport capacity to BELLUNA DOME baseball stadium and Seibuen Amusement Park. To meet diverse passenger needs, wheelchair spaces, children's seats, and in-car information displays have been installed to enhance convenience.In addition, the new trains incorporate many unique specifications designed by MHI especially for AGT system vehicles, including aluminum bodyshells, the MHI bogie,(1), a ceiling duct air conditioning system,(2) and A-MVCS (Advanced Mitsubishi Vehicle Control System). The A-MVCS in particular, in addition to the vehicle control function, has monitoring and commissioning functions for each piece of on-board equipment, allowing it to flexibly meet the needs of railway operators.Further, a large glass window has been installed in the partition wall between the driver's cab and the children's seat, allowing children to enjoy the view from the front window and driver's seat, enhancing the sense of excitement for passengers.This AGT system utilizes rubber tires for a smooth ride and low noise. In addition, as a type of clean mobility with low CO2 emissions, the system has a reduced environmental impact, supporting the realization of a decarbonized and energy-efficient world. The adoption of vehicles that combine excellent design and environmental performance also enhances the impression of the surrounding facilities.Going forward, MHI Group will continue to strive for technological innovation, and through services that safely and comfortably transport people and goods, contribute to the development of public transport that supports the lives of people around the world.(1) A bogie developed by MHI for AGT systems. It is compatible with general rubber tire operation for AGTs.(2) A system that directs air through ducts behind the ceiling to provide air conditioning.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2026 JCN Newswire. All rights reserved. www.jcnnewswire.com
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Modern Dental Group Announces 2025 Annual Results, Net Profit Surges 47.7% on Digitalization-Driven Operational Efficiency Gains ACN Newswire

Modern Dental Group Announces 2025 Annual Results, Net Profit Surges 47.7% on Digitalization-Driven Operational Efficiency Gains

RESULTS HIGHLIGHTS:- The Revenue for the year ended 31 December 2025 was approximately HK$3,736.5 million, representing an increase of approximately 11.1% as compared with the same period last year.- The Gross Profit Margin for the year ended 31 December 2025 was approximately 55.8%; the gross profit was approximately HK$2,085.0 million, representing an increase of approximately 15.9% as compared with the same period last year.- The Group’s EBITDA for the year ended 31 December 2025 was approximately HK$938.1 million, representing an increase of approximately 32.4% as compared with the same period last year.- The Group’s net profit for the year ended 31 December 2025 was approximately HK$601.2 million, representing an increase of approximately 47.7% as compared with the same period last year.- Basic earnings per share for the year ended 31 December 2025 amounted to approximately HK63.7 cents, representing an increase of approximately 47.5% as compared with the same period last year.- The Board recommended the payment of a final dividend of HK15.0 cents per ordinary share for the year ended 31 December 2025.- For the year ended 31 December 2025, the Group recorded approximately 1,039,000 cases digital solution cases produced from the Group’s production facilities in Mainland China, Thailand and Vietnam, reflecting an increase of 32.7% as compared with the same period in 2024 as a result of our clients’ continued adoption of intra-oral scanners.HONG KONG, Mar 27, 2026 - (ACN Newswire) - 26 March 2026, Modern Dental Group Limited (“Modern Dental” or “the Group”, stock code: 03600.HK), a leading global dental prosthetic device provider, announces its annual results for the year ended 31 December 2025 (“the year”).During the year ended 31 December 2025, the Group’s multi-dimensional strategies and continuous enhancement of operational efficiency and productivity as supported by the ongoing trend of digitalization in the dental industry have resulted in the Group reporting record revenues, net profit and EBITDA numbers during this period. This occurred in a period of challenging macro-economic environment with general softness in demand for dental procedures and trade war uncertainties. The Group has been proactive in its approach to deal with the unprecedented international trade environment leveraging its international production facilities located in Thailand, Vietnam and Mainland China.The global digitalization trend continues to drive consolidation within the dental prosthetics industry, enabling the Group to further expand its market share. Our ongoing digital transformation initiatives are enhancing both customer and patient experiences while improving operational efficiency, further differentiating the Group from competitors and positioning us to outperform industry peers. The Group’s underlying fundamentals remain solid, and we are well positioned to capitalize on emerging opportunities going forward.European BusinessesDuring the year ended 31 December 2025, the European market recorded a revenue of approximately HK$1,887.0 million, representing an increase of approximately HK$268.0 million as compared with the year ended 31 December 2024. This geographic market accounted for 50.5% of the Group’s total revenue. The increase of revenue from the European market was mainly attributable to the increase in sales order volume driven by the launch of new products, such as digital dentures, and our state-of-the-art digital workflows.The Group has been the frontrunner to provide comprehensive digital solutions offerings, ranging from numerous minimal invasive and aesthetic prosthetic solutions to intra-oral scanners and clear aligners, and is well positioned to capture the opportunities arising from the accelerated digitalization trend of the dental industry. The Group continues to aggressively gain market share from international and domestic competitors through our established dental ecosystem solutions with a focus on education and digitalization, which is available within close proximity to our clients; effectively meeting our clients’ high expectations through our various onshore and offshore resources. The Group is committed and will continue to equip ourselves to provide the state-of-the-art digital solutions offerings to the dental community in the market.North American BusinessesDuring the year ended 31 December 2025, the North American market recorded a revenue of approximately HK$696.4 million, representing a decrease of approximately HK$55.7 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 18.6% of the Group’s total revenue.A significant portion of our business in the North America region comprises higher-end products manufactured domestically by MicroDental Laboratories, Inc. and its subsidiaries (“MicroDental Group”). While demand for discretionary cosmetic treatments remained soft throughout 2025, our centralized digital workflows and network-wide production oversight enabled us to deliver enhanced service quality and operational efficiencies to our North American customers.Our diversified supply bases in the US, China, Vietnam and Thailand continue to provide greater flexibility to navigate US tariff uncertainties — an advantage that sets us apart from competitors. Although digitalization of imported product lines drove growth in mass market cases, implementation of the US tariff in April 2025 introduced new uncertainties and contributed to a slow growth in sales for our import-focused business unit.Greater China BusinessesFor the year ended 31 December 2025, the Greater China market recorded a revenue of approximately HK$615.4 million, representing a decrease of approximately HK$46.8 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 16.5% of the Group’s total revenue.The Mainland China market faced headwinds from the volume-based procurement policies and a prolonged period of intense price competition and the situation started to stabilize in the second half of 2025. This also led to aggressive promotions for dental implant treatments by Mainland China dental clinics in Hong Kong (which experienced a notable decrease in patient visits in Hong Kong). The Group’s has deliberately pivoted away from low-margin segments and stay focused on serving mid- and high-value customers, ensuring long-term sustainable profitability of the Group’s business.The Group is optimistic in its mid/long-term outlook for this market in particular where the latest procurement-related government measures are expected to (i) standardize the pricing of dental prosthetics and develop price transparency, which would level the playing field; (ii) allow the Group’s leading brand name and reputation to be a key consideration for its client and customer; and (iii) have the Group benefit from its large production team and its ability to allocate resources efficiently according to the customer or client.Australian BusinessesFor the year ended 31 December 2025, the Australian market recorded a revenue of approximately HK$289.1 million, representing an increase of approximately HK$24.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 7.7% of the Group’s total revenue. The increase in revenue from Australia reflected a strong uptake of new digital products driven by the digitalization trend in dental industry and the revenue contribution from the acquisition of Digital Sleep which is partially offset by the depreciation of AUD against HK$ by 2.4% compared with the year ended 31 December 2024.Through our various brands, which offer onshore-and offshore-made products, at multiple price points ranging from economy and standard to premium/boutique, the Group is able to effectively penetrate the entire Australian market. We have invested in local production capacity to provide faster service to our customers, and to provide choices around where the products are made. The Group is one of the largest players in the Australian market and is a preferred supplier to the major corporate dental groups in the market.Other MarketsOther markets primarily include Thailand, Indian Ocean countries, Malaysia, Taiwan and Singapore. For the year ended 31 December 2025, these markets recorded a revenue of approximately HK$248.9 million, representing an increase of approximately HK$182.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 6.7% of the Group’s total revenue. The increase in revenue from Other markets was primarily driven by the revenue contribution from the newly acquired Hexa Ceram.Future Prospects and StrategiesThe global macroeconomic environment remains uncertain, with geopolitical tensions and potential tariff changes continuing to create headwinds. However, the Group’s geographically diversified production footprint and global distribution network position us strongly to navigate these challenges. Unlike many competitors reliant on single-country manufacturing, our operations across China, Vietnam and Thailand (including the newly acquired Hexa Ceram) provide superior resilience and flexibility. This strategy, combined with our ability to adapt quickly to local market conditions, enables the Group to mitigate risks and capitalize on opportunities across regions.The dental industry has continued to demonstrate remarkable resilience, underpinned by irreversible demographic trends, including aging populations and increasing awareness of oral health, which drive consistent long-term demand. Building on our record 2025 performance, the Group is well placed to sustain momentum and further strengthen its market leadership.Digitalization remains an irreversible industry trend that is accelerating consolidation of the dental prosthetics industry. We are at the forefront of this transformation, with digital solution cases now representing approximately 35–40% of total volume. Our centralized digital workflows, intra-oral scanner partnerships, proprietary solutions and global education centers have enhanced operational efficiency, reduced turnaround times and delivered superior customer experiences. These initiatives create high entry barriers and will continue to drive margin expansion and market share gains in the coming years.Following the successful integration of Hexa Ceram (Thailand’s largest dental laboratory, acquired in January 2025) and Digital Sleep Design (Proprietary nylon oral appliance to treat obstructive sleep apnea), our Southeast Asian presence and specialized capabilities have been significantly strengthened. This expansion, coupled with our diversified supply bases in the US, China, Vietnam, and Thailand, provides enhanced flexibility to address potential trade and geopolitical risks while supporting faster regional delivery.Looking ahead, the Group remains committed to reinforcing its worldwide leading position through a multi-dimensional approach. We will continue to pursue selective acquisitions, joint ventures and partnerships to expand and complement our product offerings, particularly in our high-growth clear aligner, Trioclear, while strengthening our distribution and sales networks. Ongoing investments in mass-scale production facilities, AI, automation, research and development, and digital innovation will drive efficiency gains and secure our position at the forefront of the industry.About Modern Dental GroupModern Dental Group Limited (Stock code: 03600.HK) is a leading global dental prosthetics provider, distributor and consultant with a focus on providing custom-made prostheses to customers in the growing prosthetics industry. Our product portfolio is broadly categorized into three product lines: fixed prosthetic devices, such as crowns and bridges; removable prosthetic devices, such as removable dentures; and other devices, such as orthodontic devices, sports guards, clear aligners, and anti-snoring devices. Modern Dental Group has a global portfolio of respected brands, including Labocast, Permadental and Elysee Dental in Western Europe, YZJ Dental in China, Modern Dental Lab in Hong Kong, Modern Dental USA and MicroDental in the United States, Modern Dental Pacific in Australia and New Zealand, Modern Dental SG in Singapore, Modern Dental TW in Taiwan, Apex Digital Dental in Malaysia and Hexa Ceram in Thailand. We have grown these brands by providing premium and consistent quality products and superior customer service. We have more than 80 service centers in over 28 countries and serve over 35,000 customers. Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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JF SmartInvest Holdings Ltd Adjusted Profit Leaps 191.8% to RMB1.02 Billion ‘Technology + Investment Research’ Dual-Driver Strategy Delivers Remarkable Results, Overseas Expansion Ushers in a New Chapter of Globalisation ACN Newswire

JF SmartInvest Holdings Ltd Adjusted Profit Leaps 191.8% to RMB1.02 Billion ‘Technology + Investment Research’ Dual-Driver Strategy Delivers Remarkable Results, Overseas Expansion Ushers in a New Chapter of Globalisation

HIGHLIGHTS:- Total gross billings amounted to approximately RMB3,955.0 million, representing an increase of approximately 12.8% from approximately RMB3,505.9 million for the corresponding period.- Total revenue was approximately RMB3,430.1 million, representing an increase of approximately 48.7% from approximately RMB2,306.0 million for the corresponding period.- The profit attributable to Shareholders of the Group was approximately RMB921.8 million, representing an increase of approximately 238.5% from approximately RMB272.4 million for the corresponding period.- Non-HKFRS adjusted profit for the year (excluding the share-based compensation expenses) was approximately RMB1,022.5 million, representing an increase of approximately 191.8% from approximately RMB350.5 million for the corresponding period.- Taking into account the financial and cash flow positions of the Group, the Board recommends the payment of a final dividend of approximately HKD168.5 million for the year ended December 31, 2025, representing HKD0.36 per share (in cash), and the proposed final dividend is subject to consideration and approval by Shareholders at the AGM.HONG KONG, Mar 27, 2026 - (ACN Newswire) - JF SmartInvest Holdings Ltd (the “Company” ; together with its subsidiaries, the "Group" or “we”) is pleased to announce its consolidated annual results for the year ended December 31, 2025 (the “Reporting Period”). During the Reporting Period, leveraging its “technology + investment research” dual-drive strategy, the Group achieved outstanding performance. Supported by robust cash flow and profitability, the Board has proposed a final dividend of HK$0.36 per share, bringing the total dividend for the full year to approximately HK$407.4 million when combined with the interim dividend already paid, reflecting its commitment to delivering returns to shareholders.Strong Financial Performance with Substantial Profitability ImprovementDuring the Reporting Period, the Group continued to advance product innovation, AI applications, and investment research capabilities, driving solid growth across its business. Total revenue for the year reached RMB3,430.1 million, representing a YOY increase of 48.7%. Gross profit amounted to RMB2,821.0 million, up 48.9% YOY, while the gross profit margin remained at a high level of 82.2%, indicating the favourable economies of scale and earnings quality of the Group’s business model.In terms of profitability, profit attributable to equity shareholders surged by 238.5% YOY to RMB921.8 million. Excluding share-based compensation expenses, non-HKFRS adjusted profit for the year reached RMB1,022.5 million, representing a YOY increase of 191.8%, fully demonstrating the effective strategy execution and market adaptability of the Group.The Group places great emphasis on shareholder returns. The Board recommends the payment of a final dividend of approximately HKD168.5 million for the year ended December 31, 2025, representing HKD0.36 per share (in cash). Together with the interim dividend of approximately HK$238.9 million already distributed, the total dividend for 2025 will amount to approximately HK$407.4 million. The steady dividend policy fully reflects the Group’s ample cash reserves and its firm confidence in future development prospects.Continued Optimisation of Product Matrix and Enhancement of Diversified Service SystemDuring the Reporting Period, the Group continued to build a diversified product matrix, enriching its product portfolio in response to different customer needs. VIP products 'Stock Navigator, Super Investor' were steadily optimized, with the addition of several quantitative products and AI-powered products. We also launched a 24/7 AI intelligent customer service system, which significantly improved service efficiency. The live streaming system was upgraded, with sessions increasing by 36% YOY and average daily unique viewers exceeding 100,000.Relying on an integrated “AI + content + service + tools” solution, the Enjoy-Stock Pad recorded net sales volume exceeding 75,000 units during the Reporting Period. The Jiuyao Stocks launched over 80 lightweight products, converting professional investment research capabilities into standardised products. The SmartInvest APP completed its strategic transformation from a tool to a platform, with monthly active users increasing by more than 40% YOY and the 30-day retention rate remaining above 50%.The Group further enhanced its product matrix with two new products, Decision Master and Star-tier Services, filling the gap in the mid-tier product system and enabling a seamless trading service experience. Decision Master focuses on three AI+ investment research modules - themes, value investing and quantification - comprehensively enhances investment decision-making capabilities of individual investors. Star-tier Services collaborates with multiple securities brokerages and partners to create a fully integrated closed-loop ecosystem of“tools-services-trading”, serving over 50,000 users during the Reporting Period.Guided by Technological Innovation, Striving Towards “Investment Advisory Intelligent Agent 2.0”The Group regards innovation and technological R&D as its core driving force, accelerating its transformation towards “digital intelligence”, and advancing towards the era of “investment advisory intelligent agent 2.0”. During the Reporting Period, R&D expenses amounted to approximately RMB356 million, with R&D personnel reaching 624, a YOY increase of approximately 42.8%. The Group held 158 software copyrights and patents in AI, big data and product features, with 22 new items added on a year-on-year basis.The self-developed FinSphere Agent Large Model Assistant V3.0 passed the Large Model Assistant Functionality Completeness Test conducted by the China Academy of Information and Communications Technology, becoming the first large-model application in the securities industry. During the Reporting Period, it served approximately 664,000 customers with cumulative services of 22.58 million. The digital intelligent investment robo-advisor “Jiu Ge” served approximately 600,000 customers with cumulative services exceeding 19 million. The Group also launched stock diagnosis intelligent agent 4.0, AI Xiaoce Q&A assistant, and established an intelligent compliance and risk control platform covering the entire business workflow, indicating that the group's AI capabilities have gradually been implemented in core scenarios.To strengthen its technological foundation, the Group established a technology subsidiary, Jiufang Zhiqing, and set its foothold in “Shanghai Foundation Model Innovation Center”, China’s first large model innovation ecosystem community. The subsidiary serves as the Group’s core AI vehicle for operating a native service technology system, promoting the deep application of AI in scenarios such as investment research, investor education, and risk control.Deep-Rooted Investment Research as the Cornerstone, Adhering to Buyer-Side Advisory and Deepening the “1+N” Investment Research SystemThe Group continues to deepen its “1 research institute and N business lines” investment research system, with the JF Financial Research Institute as investment research hub. The Institute has established a pyramidal-structured professional talent echelon led by Chief Economist Dr. Xiao Lisheng, comprising 4 experts, 8 super-IPs and 128 professionals. As of the end of the Reporting Period, the Group had 576 employees holding securities investment advisory qualifications and 2,628 employees holding securities practitioners, maintains a leading team scale and structure in the industry.During the Reporting Period, The Institute conducted more than 300 research activities, covering more than 2,000 listed companies. The Institute authored approximately 1,200 in-depth research reports and 45 sets of thematic courses with a total duration of 2,000 minutes, continuously enhancing the professional capabilities of buyer-side consultants.Multi-Dimensional, Full-Funnel Traffic Operation to Unlock New Growth DimensionsDriven by AI technology, the Group positions refined MCN-based traffic operations as a central hub connecting users with its business, building an integrated, synergistic omni-channel traffic ecosystem comprising “public-domain MCN (multi-platform) + private-domain + proprietary APP”. On the technological front, the Group applied AIGC to restructure content production, shifting from manual creation to “human-machine collaboration” model, and established a data flywheel integrating “advertising data, model training and operational automation”. During the Reporting Period, the Group consolidated its leading position on online short-video and live streaming platforms’ operations, established a multi-platform coordinated traffic matrix, and developed a multi-tiered, high-quality content ecosystem. It also pioneered e-commerce models for the Enjoy-Stock Pad and AppStore models for the APP, driving deep integration between traffic operations and product features.Future OutlookMr. Chen Wenbin, chairman of the Board and chief executive officer of JF SmartInvest Holdings Ltd, said: “In 2025, we remained committed to the dual-drive strategy of ‘technology + investment research’. Not only did we achieve leapfrog growth in performance, but we also successfully led the industry into the era of ‘Investment Advisor Agent 2.0’. Leveraging artificial intelligence and big data technologies, we developed AI products such as the JF Robo-Advisor, FinSphere Agent and FinSphere Report, achieving industry-leading innovations and scenario-based applications, helping users accomplish the critical transition from ‘cognitive improvement’ to ‘decision optimisation’. At the same time, we transformed our professional investment research capabilities into easily accessible lightweight services, realising a strategic shift ‘from tool to platform’. We uphold the principles of rational investing, value investing and long-term investing, assisting clients in developing sound investment philosophies.“In the future, the Group will focus on four key strategic dimensions. First, deepening AI-driven empowerment across all scenarios, accelerating the iteration of AI agents and their commercialisation on the consumer side, and driving the Group’s digital and intelligent transformation. Second, leveraging Forthright Securities and Forthright Capital’s licenses, advancing the globalisation strategy by exporting the Jiufang’s core models, accelerating overseas business expansion. Meanwhile, promoting license upgrading and strategic investment layout to further improve the construction of digital asset infrastructure. Third, strengthening product-driven business diversification and synergies, deepening cooperation with licensed financial institutions such as securities brokerages, and building a service closed loop covering pre-investment, in-investment and post-investment. Fourth, continuing to optimize the customer operation system, unlocking the value of traffic through full-funnel traffic initiatives, and achieving long-term customer retention. We are dedicated to making investing simpler and more professional while enhancing investors’ sense of fulfillment in investment and wealth management.”About JF SmartInvest Holdings Ltd (Stock Code: 9636)JF SmartInvest Holdings Ltd is a new generation stock investment assistant. The Company is engaged in the provision of equity investment instruments, securities investment advisory, investor education and other services to individual investors. The products include stock quote software, the AI Stock Machine, Stock Navigator, Super Investor and Jiuyao Stocks. The Company adopts the technology + investment research model, develops JF Robo-Advisor, FinSphere Agent, FinSphere Report and other products based on artificial intelligence (AI) and big data technology, which are applied to the industry in terms of innovative practice and scenario application.For enquiries, please contact:Financial PR (HK) LimitedEmail: ir@financialpr.hkTel: 852 2610 0846Fax: 852 2610 0842 Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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How to Choose the Right Savings Account for Your Money Goals in Singapore ACN Newswire

How to Choose the Right Savings Account for Your Money Goals in Singapore

SINGAPORE, Mar 27, 2026 - (ACN Newswire) - Choosing where to place your savings in Singapore is an important financial decision that requires careful consideration. With many banks offering different types of accounts, it is easy to get confused. However, picking the right one is the first step to reaching your financial goals, whether you are saving for a dream wedding, a new home, or a retirement fund.The good news is that you no longer need to spend a whole afternoon waiting at a bank branch. You can now open a bank account online in just a few minutes using your phone or computer. Here is a simple guide to help you choose the best account for your needs in 2026.Identify Your Financial HabitsBefore focusing on interest rates, consider how you manage your money on a daily basis. Savings accounts in Singapore usually fall into two categories:The Active Saver: These accounts give you high interest rates, but you have to make a few mandatory transactions each month. Usually, you need to credit your salary and spend a set amount on your credit card.The Passive Saver: These accounts help you earn bonus interest just for keeping your money in the account and letting it grow. You do not need to worry about credit card spending or paying bills.Compare Interest RatesBefore opening a bank account online, make sure you compare the interest rates. Many basic accounts offer low interest rates. To make your money grow, you should look for bonus interest.For example, a high-interest account can offer between 2% and 5% depending on the rules you follow. If you have SGD 50,000, the difference between a basic account and a high-interest one could be hundreds of dollars in extra cash every year. Always check the effective interest rate, which tells you the real amount you will earn after all the levels are counted.Look for Welcome PromotionsBanks in Singapore are always competing for your business. When you open a bank account online, you can often grab a welcome gift, such as cash credits or rewards. These promotions are a great way to get a head start on your savings. Just make sure to check the dates, as many of these flash deals only last for a few months.Check the Fees and MinimumsEven a great account can lose you money if you are not careful about fees. Before you sign up, check for these three things:Minimum balance: Most accounts require maintaining a certain amount of money in the account at all times. If the balance drops below this limit, the bank may charge you a monthly fee.Initial deposit: Some accounts require at least SGD 1,000 to get started.ATM access: Make sure the bank has plenty of ATMs near your home or office so you do not get charged for using the machine of another bank.Open an Account OnlineOnce you have picked the right account, the final step is to fill out your application. In Singapore, you can use Singpass MyInfo to fill out your application automatically.When you open a bank account online, your details, such as your NRIC, address, and income, are pulled directly from the government database, thus reducing paperwork. Most accounts are approved almost instantly, and you can start using your new digital card right away.Final ThoughtsChoosing a savings account is not just about finding the highest interest rate. It is about finding the one that fits how you live. If you are a busy professional who already uses a credit card, an active account is perfect. If you just want to set your money aside and forget it, a passive account is better.By taking 10 minutes to compare your options today, you can ensure that every dollar you earn works as hard as you do.Disclaimer: This article is for general information only and does not have any regard to the specific investment objectives, financial situation and particular needs of any specific person. The views expressed in this article are solely those of the author. This article shall not be regarded as an offer, recommendation, solicitation or advice. You may wish to consult your own professional advisers about this article, in particular, a financial professional before making financial decisions. Any past events, trends and/or performance referred to in this article may not necessarily be indicative of future events, trends or performance. This article is based on certain assumptions and reflects prevailing conditions as at the time of publication, which are subject to change at any time without notice. The author and publisher of this article as well as any other parties associated with this article make no representation or warranty of any kind, whether express, implied or statutory, in respect of this article and accept no liability or responsibility for the completeness or accuracy of this article or any error, inaccuracy or omission relating to this article and/or any consequence, injury, loss or damage howsoever suffered by any person relating to this article, in particular, arising from any reliance by any person on this article. Publishers or platforms may be compensated for access to third party websites.Contact Information:Name: Sonakshi MurzeEmail: Sonakshi.murze@iquanti.comJob Title: ManagerSOURCE: iQuanti Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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Fujitsu develops high-sensitivity, high-resolution infrared sensor to expand monitoring capabilities in defense and disaster prevention JCN Newswire

Fujitsu develops high-sensitivity, high-resolution infrared sensor to expand monitoring capabilities in defense and disaster prevention

KAWASAKI, Japan, Mar 27, 2026 - (JCN Newswire) - Fujitsu today announced the development of a world-leading, high-sensitivity and high-resolution infrared sensor to expand monitoring capabilities in the defense and disaster prevention fields. This sensor is a Type-II superlattice (T2SL) infrared sensor with over 1 million pixels, capable of detecting both mid-wavelength infrared (MWIR) and long-wavelength infrared (LWIR) light. Its high-sensitivity allows it to clearly capture minute thermal differences of 0.05°C or less, enabling high-precision monitoring day and night. This over 1-megapixel dual-band T2SL infrared sensor is the first of its kind in the world.The newly developed technology boasts dramatically enhanced detection and identification performance, with applications spanning a wide range of fields. For example, when applied to optical sensor systems mounted on satellites or aircraft, it can contribute to the creation of new value across diverse areas, including early assessment of disaster situations and environmental monitoring.Integrating this sensor into monitoring devices for defense and disaster prevention enables accurate detection of thermal changes, such as identifying precursors to human activity or object movement, locating people during disasters, detecting early forest fires, and monitoring tsunamis. This contributes to improving information gathering capabilities and strengthening defense and disaster prevention. Additionally, by visualizing thermal distribution and changes over time with exceptional precision, the sensor is anticipated to play a vital role in tackling societal issues like infrastructure inspection and problems with analytical equipment, while also driving progress in scientific research.This technology was developed under contract as part of the "PROTOTYPE OF WIDE BAND AND HIGH RESPONSIVITY PHOTO-DETECTORS" from Acquisition Technology & Logistics Agency (ATLA), Japan Ministry of Defense, to which Fujitsu has completed delivery of the prototype sensor.Starting in fiscal year 2026, Fujitsu plans to leverage the manufacturing technology of this sensor to develop new products and market them for use in monitoring cameras.BackgroundIn the security sector, which underpins a safe and secure society, there is a demand for advanced sensing technologies that can detect various threats early and accurately capture their precursors. However, with the diversification of monitoring scenarios and the increasing complexity of targets, there is a need for even higher resolution sensors and improved identification capabilities through simultaneous detection of multiple wavelengths. The ATLA initiated a research prototype project to establish technology that enables target detection and identification over longer distances and wider areas than existing systems. Fujitsu, which has developed and mass-produced high-sensitivity infrared sensors, was awarded this project and has now successfully completed its development.Overview of the developed sensorInfrared sensors capture infrared radiation spontaneously emitted by objects with heat, visualizing their surface temperature distribution. Fujitsu has leveraged the characteristics of T2SL, a compound semiconductor with a superlattice structure that allows for material property control, to develop a unique dual-band sensor. The superlattice structure, where different semiconductor materials are layered at the nanometer (one billionth of a meter) level, offers high sensitivity, as well as excellent control over detection wavelengths and manufacturability. By selecting a combination of semiconductor materials with a large energy offset in their band structure (i.e., Type-II Superlattice, T2SL), it is possible to detect infrared light, which has lower energy than visible light.This sensor can detect MWIR and LWIR wavelength bands, with high-sensitivity capable of detecting temperature differences of 0.05°C or less. By simultaneously detecting two wavelengths with a single pixel, it can accurately detect and identify targets that would otherwise be obscured by background noise during detection with single-wavelength sensors. Furthermore, by advancing miniaturization of elements through the development of manufacturing processes and mounting technologies suitable for delicate T2SL materials, Fujitsu has achieved high-resolution with over 1 million pixels, enabling the capture of more distant targets.This infrared sensor, simultaneously achieving high-sensitivity, high-resolution, and dual-band detection, is suitable for monitoring applications in defense, disaster prevention, and other fields requiring high discrimination performance.Furthermore, this world-first technology from Fujitsu will drive further advancements in the sensitivity, multi-band and high-resolution capabilities of conventional infrared sensors, enabling a diverse range of product developments.Figure: Dual-band T2SL infrared sensor and example imagesAbout FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2026 JCN Newswire. All rights reserved. www.jcnnewswire.com
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Hua Medicine Announces 2025 Annual Results ACN Newswire

Hua Medicine Announces 2025 Annual Results

- Annual sales of HuaTangNing exceeded 4 million packs, a year-on-year increase of 91%, with revenues reaching RMB 492.9 million, a year-on-year increase of 93%, marking outstanding results from the Company’s fully independent commercialization operation.- Delivered record financial performance, with profit before tax reaching RMB 1,106.4 million; maintained a robust bank balance and cash position of RMB 1,092.3 million at year-end, laying a solid foundation for sustainable operations and growth.- Gross margins rose to 56.9%, and selling expenses as a percentage of revenue were optimized to 33.6% from 59.9%, significantly enhancing profitability.- HuaTangNing renewed its listing in the new National Reimbursement Drug List (NRDL) at the same price in 2025 for the calendar years 2026 and 2027, reaffirming its clinical and innovative value.- With the approval of PTE, market exclusivity in China granted another 5 years to April 2034, further strengthening commercial certainty.- Dorzagliatin was approved for commercialization in Hong Kong as HYHOMSIS®, accelerating its global expansion toward South-East Asia.- Multiple real-world evidence published to demonstrate therapeutic advantage of dorzagliatin.- Continuous expansion of therapeutic potential of glucose homeostasis and initiation of new first-in-disease indications study covering diabetes prevention, rare diseases, mild cognition impairment and frailty.SHANGHAI, Mar 27, 2026 - (ACN Newswire) – Hua Medicine ("the Company", Hong Kong Stock Exchange Stock Code: 2552) announces the audited consolidated results of the Company and its subsidiaries for the year ended December 31, 2025 (the “Reporting Period”). During the Reporting Period, the commercialization of HuaTangNing (dorzagliatin tablets), the Company’s core product – the global first-in-class innovative anti-diabetes medicine, glucokinase activator (GKA) – advanced comprehensively across all fronts, the Company’s independent commercialization team was efficiently and seamlessly established in its first year of operations, the Company’s R&D pipeline continued to be enriched, and the Company’s financial performance achieved a historic breakthrough, successfully entering a new stage of profitability, injecting strong momentum into the innovative development of the global diabetes treatment field.Dr. Li CHEN, Founder and CEO of Hua Medicine, stated: “2025 is a remarkable year in the commercialization operation of Hua Medicine. The Company has successfully advanced from R&D to commercialization driven organization and achieved the fully independent capacity in commercialization of global first in class novel glucose homeostasis regulator HuaTangNing. With strong market execution and product competitiveness, we have achieved nearly triple-digit growth in sales volume and revenue over 2024 when the commercialization was farmed out to sales and marketing partners. At the same time, the Company has made key progress in global market expansion through registration of drozagliatin in Hong Kong and position it toward 700 M population in south-east Asia. We continue to expand the clinical application of glucose homeostasis regulation technology and engage in new indications such as early-stage Alzheimer’s disease and Frailty. The first-in-disease efforts in GCK-MODY and Frailty set the new innovation course of Hua Medicine in the next 5 years.” Business Highlights and Operational Progress- Fully Powered Commercialization, Historic Breakthrough in ProfitabilityOn January 1, 2025, the Company assumed full responsibility for the commercialization of HuaTangNing, allowing the company to consolidate both operational and strategic control over market execution in China. The Company successfully built a professional sales team covering 10 sales regions around the country, focusing on marketing, medical affairs and commercial operation. Through an AI-empowered digital commercialization platform, operational efficiency and sales productivity were greatly enhanced, injecting new vitality into the Company’s commercial development.Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. Since its launch in October 2022, HuaTangNing has been prescribed to over 500,000 patients through 3,000+ hospitals, community centers, pharmacies and online channels.Sales performance exceeded expectations, with 4.011 million packs of HuaTangNing sold during the reporting period, representing a 91% increase over the fiscal year 2024. This growth was achieved at the same price for both periods, underscoring strong demand and successful execution of Hua’s commercial strategy.In terms of profitability, the Company’s gross profit reached approximately RMB280.4 million, a year-on-year increase of 125%. Thanks to expanded production scale and optimized manufacturing processes, the Company’s gross margin improved to 56.9%, increasing by 8.2 percentage points as compared to 48.7% for the year of 2024. Selling expenses increased only by RMB12.3 million to RMB165.5 million, reflecting a significant positive trend towards profitability when our selling expenses in the 2025 fiscal year represents only 33.6% of revenue, whereas in the 2024 fiscal year, our selling expenses represented approximately 59.9% of revenue. In fiscal year 2025, our commercialization efforts achieved profits of approximately RMB114.9 million (as defined by gross profits less selling expenses). Although we expect to continue to increase personnel to our commercialization team, we expect this profitability trend in our commercial operations in mainland China to continue.Following the termination of the collaboration with Bayer at the end of 2024, dorzagliatin achieved a record-high sales volume. Profit before tax increased to RMB1,106.4 million for the fiscal year 2025. We ended fiscal year 2025 with a cash position of approximately RMB1,092.3 million.- Accelerated Global Layout, Strengthened Core Rights and InterestsThe Company took a key step in global expansion. On February 27, 2026, dorzagliatin (trade name: MYHOMSIS®, was successfully approved for marketing by the Hong Kong regulatory authority. The Company plans to officially launch the product in the Hong Kong market by the middle of 2026 and further expand to Asian regions. In addition, the Company submitted a new drug registration application in Macau in 2025.The Company also made new progress in intellectual property protection. In February 2026, the patent term extension (PTE) application for dorzagliatin was formally approved by the China National Intellectual Property Administration, thereby the core patent protection period of dorzagliatin extended to April 2034 and an additional 5-year market exclusivity obtained, which provides a strong guarantee for the product’s long-term market competition.In 2025, dorzagliatin was recognized as national innovation and an effective therapy for chronic diseases by the regulatory authorities in China. Accordingly, the same NRDL price was offered for the calendar years 2026 and 2027. Reimbursement coverage under the NRDL has significantly increased accessibility, especially in Tier 2 and Tier 3 hospitals, and played a critical role in accelerating patient adoption. The Company will continue to safeguard the product’s market competitiveness and patient accessibility and accelerate the popularization of the drug among patients.- Advancement of Real-World Studies, Continuous Validation of Clinical ValueReal-world evidence (RWE) studies continue to corroborate the key role of dorzagliatin in improving glucose-dependent pancreatic islet secretion function, and demonstrate its efficacy in diabetes prevention, remission, and delaying or preventing diabetes complications.The RWE study sponsored by Hua Medicine HMM0701 with 380 T2D patients was fully enrolled in 2025. The interim analysis, as reported at the 2025 American Diabetes Association (ADA), showed that 86% of such patients were taking two or more antidiabetic drugs and 41% of such patients were using insulin. After a 6-month treatment, a significant improvement of glycemic control was observed with HbA1c reduction from 8.1% to 7.3% with the mean time-in-range (TIR) levels increasing to over 70%. Thus far, the studies have demonstrated that when dorzagliatin is administered in combination with other antidiabetic drugs, such patients have experienced significantly improved post-meal glucose levels and improved β-cell function.Separately, a mechanistic study with dorzagliatin (employing double-tracer measurement) was conducted in the United States to provide scientific evidence of hepatic glycogen formation in T2D patients with an average of 17 years of diagnosed diabetes. In this study, patients were treated with dorzagliatin twice daily for 6 weeks. The results showed that dorzagliatin increased direct glucose flux to hepatic glycogen implying the improvement of restoration of hepatic Glucokinase (GK) function. Together with the clinical research data that dorzagliatin improves early phase insulin release and GLP-1 secretion, recovery of hepatic glycogen synthesis in T2D patients offers an important path in controlling post-meal glucose excursion and provides a unique opportunity in controlling diabetes complications, such as diabetes kidney diseases and mild cognition impairment.The RWE sponsored by Hua Medicine (HMM0601) has completed clinical trials with over 2,000 subjects, with average diabetes duration of 7.9 years and above 30% having disease duration more than 10 years. The initial results suggest that dorzagliatin is safe and well tolerated in Chinese T2DM patients. There were no new adverse effects observed in the study and the incident rate remains as low as what was observed in Phase III clinical trials. Patient adherence was generally high, with a mean adherence rate of approximately 95%. In this study, 80% of the participants have used one or more oral anti-diabetes medicine, and 20% used insulin. Dorzagliatin demonstrated good efficacy and safety not only in the overall population but also in elderly, obese, and hyperglycemic patient populations, whether used as monotherapy or in combination with metformin, SGLT2 inhibitors, insulin, and other medications. The topline results will be reported at the 2026 American Diabetes Association.- Deepened Clinical R&D, Continuous Expansion of New IndicationsNew Indication for Dorzagliatin – MODY-2 Patients.Medical experts in mainland China and Hong Kong have conducted independent clinical and preclinical studies of dorzagliatin for MODY-2 treatment. MODY-2, also called GCK-MODY, is a monogenic disease in which patients have a genetic defect of glucokinase gene (GCK) which results in elevated blood glucose and significant reduction of the second phase insulin secretion. The population of GCK-MODY patients is approximately 1.7 million in China. These patients are diagnosed with diabetes at a young age and represent an unmet medical need given that currently available medications are not effective. In clinical studies with MODY-2 patients, China investigators have reported that dorzagliatin is effective in reducing blood glucose levels to normal levels in MODY-2 patients who previously failed to manage their elevated blood glucose levels when treated with metformin, TZD, DPP-IV inhibitors, and SGLT-2 inhibitors. Additional results demonstrated that a single dose of dorzagliatin improved overall glucose sensitivity and second phase insulin secretion significantly in GCK-MODY patients, suggesting a unique mechanism of action of dorzagliatin to regulate GLP-1 secretion. Based on such results, Hua Medicine has communicated and reached a consensus with the CDE at NMPA to file the IND submission of dorzagliatin for MODY-2 patients in 2026.Dorzagliatin for Diabetes Prevention.Prevention of diabetes is an important focus at Hua Medicine. There are approximately 1.12 billion people living with prediabetes worldwide. We have initiated SENSITIZE 3 clinical study in Hong Kong in pre-diabetic (IGT) subjects and in early diabetes patients. These studies represent first-in-disease studies. In this double-blinded placebo-controlled study, we will evaluate the blood glucose management and pancreatic function under IVGTT and OGTT conditions to better define the clinical treatment baseline and endpoints. We expect to complete this study in 2026 and explore the opportunity to file IND applications of dorzagliatin for diabetes prevention in China and Asian Pacific regions thereafter. Dorzagliatin for Neurodegenerative Diseases.MCI shows approximately 15.5% prevalence among elderly people in China and approximately 22% in the US, and is common in T2D patients with a 45% incidence rate. The development of dorzagliatin for neurodegenerative disease is a new focus in our drug discovery efforts. Through the Genome-Wide Association Study (GWAS) and Mendelian Randomization (MR) study, we have realized the important role of GCK gene activation in the prevention of memory loss and cognitive impairment in humans. It has also come to our attention that post-meal glucose excursion is closely related to Alzheimer disease and dementia. The bio-energy balance in the brain is largely dependent on the glucose homeostasis control in the peripheral organ and the neural network communication in the central and peripheral system via spatial temporal management. Impaired glucose homeostasis and diabetes conditions result in a reduction of glucose transporter expression and insulin receptor expression in the brain, which can be prevented by low dose dorzagliatin. We have realized the potential of dorzagliatin in the treatment of mild cognitive impairment (MCI) and will initiate these first-in-disease clinical studies in the future.Dorzagliatin for Frailty.Frailty is an age-related geriatric syndrome characterized by reduced tolerance to internal and external stressors. Approximately 17% of Americans and 11% of Asians over the age of 50 suffer from frailty, while pre-frailty affects roughly 50% and 47% of these populations, respectively. It is not a single-organ disease, but the consequence of dysregulated multisystem homeostasis. Genetic evidence supports the causal effects of glucokinase (GK) activation on lowering frailty risk. We plan to initiate clinical studies in the future to advance dorzagliatin’s application in frailty.Development of combination therapy for diabetes and complications.Dorzagliatin rescues pancreatic function in glucose insulin secretion and GLP-1 secretion, as evidenced by clinical and basic research results. It also improves hepatic insulin sensitivity and reduces hepatic insulin resistance through recovery of hepatic glycogen synthesis in T2D patients. The combination of dorzagliatin with DPP-IV inhibitors, SGLT-2 inhibitors, and GLP-1 agonists have demonstrated effective regulation of lipid metabolism. Studies in combination with anticancer PI3K inhibitors have also offered unique benefits for glucose homeostasis management.- Diversified Product Pipeline, Innovative Layout for Future GrowthHua Medicine continues to enrich its pipeline layout based on core products. The Company has accelerated the R&D of a fixed-dose combination (FDC) of dorzagliatin and metformin as a twice-daily therapy for Type 2 diabetes patients with inadequate glycemic control on metformin alone, to further improve patient medication compliance. The product is supported by the strong results of the loose-dose combination in both Phase III clinical trials and real-world use. The Company has submitted an IND application to NMPA, and the GMP commercial manufacturing process has been successfully carried out, preparing for the pivotal bioequivalence study for NDA filing in 2027. Clinical studies have shown that the combination of dorzagliatin and metformin can better control blood glucose, reduce postprandial blood glucose and improve fasting blood glucose, providing new clinical value for optimizing blood glucose homeostasis endpoints.We have advanced our 2nd generation GKA as a once daily therapy for patients with obesity, leveraging dorzagliatin effects in improved glucose-stimulated GLP-1 secretion in the pancreas and in the intestine. The MAD study of the 2nd generation GKA was initiated in the United States with first-patient-in in December 2025, and we expect to report topline data by the middle of 2026.Meanwhile, the Company is also exploring combination therapy regimens of dorzagliatin with GLP-1 receptor agonists, SGLT-2 inhibitors and other drugs. In a recently published clinical trial in China, researchers reported the superior benefits of our dorzagliatin in combination with semaglutide as compared to semaglutide alone in a 12-week study. The combination group showed superior results across several key measures, including glycemic control, bodyweight related indicators and β-cell function.Financial Summary- Revenue generated by the Company was approximately RMB 492.9 million from the sale of approximately 4.011 million packs of HuaTangNing, increases of approximately 93% and 91% respectively, as compared with the year ended December 31, 2024.- Gross profit generated by the Company for the year ended December 31, 2025, was approximately RMB280.4 million, representing an increase of approximately 125%, as compared with the year ended December 31, 2024, and gross margins rose to 56.9%.- Profit before tax increased by approximately 542% to approximately RMB1,106.4 million for the year ended December 31, 2025, as compared with the year ended December 31, 2024.- Bank balances and cash position was approximately RMB1,092.3 million as of December 31, 2025.- Expenditures incurred by the Company for the year ended December 31, 2025, were approximately RMB433.4 million.Forward-Looking StatementsThis document contains statements regarding Hua Medicine's and its products' future expectations, plans and prospects. Such forward-looking statements relate only to events or information as of the date on which the statements are made in this document and are subject to change in light of future developments. Except as required by law, the Company shall not be obligated to update or publicly revise any forward-looking statements or unforeseen events after the date of such statements, whether as a result of new information, future events or other circumstances. Please read this document carefully and understand that actual future performance or results of the Company may differ materially from expectations due to various risks, uncertainties or other statutory requirements.About Hua MedicineHua Medicine (The “Company”) is an innovative drug development and commercialization company based in Shanghai, China, with companies in the United States and Hong Kong. Hua Medicine focuses on developing novel therapies for patients with unmet medical needs worldwide. Based on global resources, Hua Medicine teams up with global high-calibre people to develop breakthrough technologies and products, which contribute to innovation in diabetes care. Hua Medicine's cornerstone product HuaTangNing (dorzagliatin tablets), targets the glucose sensor glucokinase, restores glucose sensitivity in T2D patients, and stabilizes imbalances in blood glucose levels in patients. HuaTangNing was approved by the National Medical Products Administration (NMPA) of China on September 30th, 2022. It can be used alone or in combination with metformin for adult T2D patients. For patients with chronic kidney disease (CKD), no dose adjustment is required. It is an oral hypoglycemic drug that can be used for patients with Type 2 diabetes with renal function impairment. In February 2026, dorzagliatin (Trade name: MYHOMSIS®,) was approved for marketing by the Pharmaceutical Services of the Department of Health of the Government of the Hong Kong Special Administrative Region of China.For more informationHua MedicineWebsite: www.huamedicine.comInvestorsEmail: ir@huamedicine.comMediaEmail: pr@huamedicine.com Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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IGT Menjadi Perusahaan Game Terbaru yang Mengumumkan Pemecatan Seiring Meningkatnya Ketidakpastian Makroekonomi iGame

IGT Menjadi Perusahaan Game Terbaru yang Mengumumkan Pemecatan Seiring Meningkatnya Ketidakpastian Makroekonomi

(AsiaGameHub) - IGT yang baru saja direformasi mengumumkan pemutusan hubungan kerja (PHK) pada Senin yang mempengaruhi sekitar 700 karyawan, atau sekitar 10% dari tenaga kerja globalnya. Perusahaan game ini menjadi yang terbaru untuk melakukan pemotongan tenaga kerja menghadapi angin topan ekonomi makro. Rincian jabatan dan lokasi tidak diungkapkan. Menurut memo internal yang dilaporkan oleh Las Vegas Review-Journal, CEO IGT Hector Fernandez memberitahu staf bahwa PHK ini tidak terkait dengan kinerja. Sebaliknya, ini adalah "bagian dari upaya untuk menyederhanakan struktur kita, mengurangi duplikasi dan memungkinkan kita bergerak dengan kejelasan dan kecepatan yang lebih besar". "Yang penting sekarang adalah bagaimana kita maju bersama: saling mendukung, fokus pada prioritas kita dan melanjutkan pekerjaan yang akan menentukan babak selanjutnya dari perusahaan kita," lanjut Fernandez. "Kita berkumpul untuk membangun perusahaan yang dapat memimpin di industri yang berkembang pesat, dan saya tetap percaya pada peluang itu dan kekuatan tim kita." IGT baru saja menyelesaikan merger senilai 6,3 miliar dolar AS dengan Everi Holdings, dan entitas gabungan sekarang menjadi swasta di bawah Apollo Global Management. Kedua pemasok ini sebelumnya telah menyetujui merger independen sebelum Apollo mengakuisisi keduanya. Sebagai bagian dari kesepakatan tersebut, bisnis game IGT digabungkan dengan segmen teknologi keuangan Everi – divisi lotere sebelumnya IGT dipisahkan menjadi perusahaan publik terpisah, Brightstar Lottery. PHK ini tidak mengejutkan, mengingat merger yang kompleks ini pastinya akan menghasilkan perubahan lebih dari hanya pemisahan divisi lotere. Namun ini adalah indikasi terbaru bahwa perusahaan game merasakan tekanan saat kuartal pertama 2026 mendekati penutupan. Pasaran yang Tidak Pasti di Seluruh Industri Sejak Presiden AS Donald Trump menjabat untuk jabatan keduanya pada Januari lalu, ekonomi AS telah mengalami fluktuasi drastis akibat peningkatan tarif, penutupan pemerintah, inflasi yang bertahan, dan yang paling baru, perang yang membesar dengan Iran. Untuk industri konsumen diskresioner seperti game, dampak ini menyentuh hampir setiap segmen. Tarif meningkatkan biaya konstruksi untuk operator dan biaya produksi untuk pemasok; penutupan pemerintah dan geopolitik mempengaruhi perjalanan dan pengeluaran konsumen bagi operator; dan inflasi yang bertahan menjaga suku bunga tetap tinggi, menekan aktivitas M&A dan pembiayaan ulang hutang untuk seluruh industri. Perusahaan game saat ini memiliki kelipatan usaha yang lebih rendah dan rasio utang terhadap EBTIDA yang lebih tinggi dibandingkan rata-rata pasar, menurut data dari New York University. Untuk pemasok seperti IGT, semakin sulit untuk meramalkan atau berkinerja baik ketika biaya bahan baku dan perdagangan tidak pasti dari saat ke saat. Salah satu reaksi terhadap ketidakpastian adalah mengurangi tenaga kerja, namun hal ini juga berisiko bersifat pendek pikiran. "The hard part is that we’re not thinking six months, nine months, 12 months down the road. The long-term effect [of tariffs and economic uncertainty] is unclear," Daron Dorsey, CEO of the Association of Gaming Equipment Manufacturers, told iGB last October. "No one necessarily knows when things will become more stable and consistent. So no one is making long-term strategic decisions, because things might change again four months from now. Then that might undo something that you do today. And that’s the world they’re living in right now." PHK di Beberapa Perusahaan Tahun Ini Selain IGT, beberapa nama industri terkenal lainnya telah mengumumkan PHK tahun ini. Mungkin yang paling signifikan dalam lingkupnya adalah Underdog, yang memecat 20% tenaga kerjanya pada akhir Februari. Pemula olahraga fantasi ini sedang beralih ke pasar prediksi, yang, sebagai produk nasional, membutuhkan tenaga kerja lebih sedikit dibandingkan kerangka kerja per negara bagian. "It’s simply a different operation, and the changes we made are a part of that transition," Underdog CEO Jeremy Levine said in a statement. Demikian pula, DraftKings juga mengumumkan PHK pada Februari, meskipun jumlah totalnya tidak diungkapkan. Dalam sebuah pernyataan, perusahaan mengatakan bahwa mereka telah "memutuskan untuk mereorganisasi beberapa tim untuk lebih menyesuaikan tenaga kerja mereka dengan prioritas terpenting dan area investasi untuk perusahaan". Analis Citizens Jordan Bender menggunakan perkiraan 5% dari tenaga kerja DraftKings dalam catatan penelitiannya, yang katanya dapat menghemat sekitar 30 juta dolar AS untuk perusahaan. "We believe the current round of restructuring could have been larger or more impactful for the model if not for the push into prediction markets based on the CEO’s push to implement AI throughout the organisation for internal and external functions," Bender wrote to investors. Di dunia iGaming, pemasok Bragg Gaming memecat 12% tenaga kerjanya pada Januari. Langkah ini dimaksudkan untuk "realign" perusahaan untuk pertumbuhan masa depan sambil menghasilkan penghematan biaya sekitar 4,5 juta euro. "Our strategic restructuring is designed to capitalise on our strong foundation. It will position us extremely well for organic growth and concurrent market consolidation opportunities," Bragg CEO Matevz Mazij said in a statement. Industri Kasino Kuat namun Tantangan Tetap Ada Industri kasino darat sejauh ini menghindari PHK massal, namun prospeknya masih tidak pasti, terutama di Las Vegas. Pada kuartal empat tahun lalu, Indeks Kepercayaan Bisnis Nevada Selatan UNLV turun ke level terendah sejak Resesi Besar, didorong turun oleh sentimen perekrutan yang rendah dan ekspektasi masa depan. Tidak ada operator besar yang mengumumkan PHK besar tahun ini, namun Nevada Selatan secara keseluruhan telah mengalami pengurangan pekerjaan. Menurut Nevada Department of Employment, Training and Rehabilitation, area metropolitan Las Vegas menyelesaikan tahun 2025 dengan hampir 10.000 pekerjaan lebih sedikit dibandingkan Desember 2024. Tingkat pengangguran yang disesuaikan musiman negara bagian sebesar 5,2% sedikit di atas rata-rata nasional sebesar 4,4%. Beberapa kasino Las Vegas telah mengkonfirmasi PHK dari pertengahan 2024 hingga pertengahan 2025. Ini termasuk Rio Hotel and Casino, the Venetian and Palazzo, dan Resorts World Las Vegas. Selain itu, MGM Resorts menghapus layanan concierge di enam dari sembilan kasino Stripnya pada April lalu. "The fact of the matter is that we’re always managing our labour expenses, and you’re seeing a reflection of that," MGM CFO Jonathan Halkyard said on the company’s Q1 2025 earnings call. Jess MarquezJess telah meliput industri game global sejak 2022. Seorang warga asli Reno, Nevada, dia ingin menegaskan bahwa itu adalah Ne-va-da, bukan Ne-VAH-da. Artikel ini disediakan oleh penyedia konten pihak ketiga. AsiaGameHub (https://asiagamehub.com/) tidak memberikan jaminan atau pernyataan apa pun terkait isinya. Kategori: Berita Terkini, Pembaruan Umum AsiaGameHub menyediakan layanan distribusi iGaming yang ditargetkan untuk perusahaan dan organisasi, dengan menghubungkan lebih dari 3.000 media premium di Asia dan lebih dari 80.000 influencer spesialis. Platform ini menjadi jembatan utama untuk distribusi konten iGaming, kasino, dan eSports di seluruh kawasan ASEAN.
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Unisound Posts Strong First Annual Results Since Listing: Revenue Surges Nearly 30%, H2 Loss Narrows Significantly by Over 90%, Profitability in Sight, Charting a New Course in Native Agentic AI! ACN Newswire

Unisound Posts Strong First Annual Results Since Listing: Revenue Surges Nearly 30%, H2 Loss Narrows Significantly by Over 90%, Profitability in Sight, Charting a New Course in Native Agentic AI!

HONG KONG, Mar 27, 2026 - (ACN Newswire) – 26 March, Unisound (09678.HK) announced its audited annual results for the year ended December 31, 2025. As the Company's first annual results announcement since listing, it underscores strong growth momentum and continued improvement in its financial profile.Revenue Mix Continues to Improve, with Faster Growth in H2For the full year of 2025, Unisound achieved total revenue of $175 million, representing a year-on-year (YoY) increase of 29%. Revenue in the second half of the year increased by 33% YoY to $117 million.It is worth noting that the Company's large language model (LLM) business generated a full-year revenue of $88.43 million, surging by over 10 times YoY. In particular, this business contributed approximately $72.49 million in H2 revenue, five times the level recorded in H1, demonstrating a compelling capacity for large-scale commercial application.Losses Narrowed Significantly, Making the Path to Profitability Increasingly ClearAlongside the rapid revenue growth, the Company's losses improved markedly. In the second half of 2025, the Company's net loss narrowed by 84% YoY, and its adjusted loss narrowed by 92% YoY, approaching break-even. This reflects the Company's ongoing improvements in cost control and operational efficiency.Simultaneously, some of the Company's operating metrics saw marked improvement. The adjusted expense ratio declined significantly by 10 percentage points YoY, while selling expenses decreased rather than increased and accounted for only 5.4%, highlighting a clear improvement in cost-to-efficiency ratio. In 2025, revenue per employee reached $365,300, up 25% YoY from $292,900 in 2024. Employee productivity continued to lead the industry, clearly underscoring the Company's core strengths in technology-driven, lean operations.Dual-Engine Strategy Gains Traction, with AI in Healthcare and AI in Daily Life Advancing in TandemIn 2025, driven by both technological breakthroughs and policy tailwinds, global demand for AI continued to rise. Unisound adhered to its "Strong Foundation Model + Deep Application" strategy, continued to strengthen its multimodal technology foundation, and drove the continuous elevation of the global influence of its proprietary large model matrix in fields such as healthcare, speech, and OCR.On the commercialization front, the Company leveraged its AI-native organization to accelerate business execution, and its dual-engine strategy in AI in Healthcare and AI in Daily Life delivered notable results. During the reporting period:The AI in Daily Life business achieved revenue of $140 million, a YoY increase of 30.8%. Among this, the Transportation segment recorded nearly 40% YoY growth. At present, AI agent applications based on the Shanhai large model have been deployed in more than 10 cities, including Qingdao, Ningbo, Shenzhen and Nanning. In addition, cumulative AI chip shipments exceeded 110 million units, further validating the Company's scale capabilities in endpoint AI products.The AI in Healthcare business achieved revenue of $35.38 million, a YoY increase of 22.3%, with average revenue per customer growing by 53.2% YoY. In 2025, over 70% of the hospitals the Company collaborated with were tertiary hospitals, and more than one-third of customers had maintained continuous cooperation for over three years. The medical-record entry and generation products powered by the medical large model delivered a 10-fold YoY increase in full-annual medical record generation at a single campus of a leading Class III hospital. The commercial insurance AI agent platform recorded a 37-fold YoY increase in case processing volume. In deep cooperation with a leading insurance group, the expense control rate was effectively raised to approximately 20%, delivering more than $145 million in incremental cost management compared with traditional review methods, comprehensively empowering insurance institutions to refine their medical risk management operations.Continued R&D Investment Strengthens the Technology MoatTo consolidate its industry-leading position, the Company continued to invest heavily in R&D in 2025. Full-year R&D expenses exceeded $55.09 million, accounting for 75% of the Company's adjusted operating expenses, while R&D personnel accounted for 69% of the total workforce. This sustained investment drove breakthroughs across multiple technology areas. For example, in the MedBench 4.0 evaluation, the Company ranked first place in three technical paradigms: "Medical AI Agent," "Medical Large Language Model," and "Medical Multimodal Large Model," earning a "Triple Crown."Outlook: Deepening the Technological Foundation and Expanding Application BoundariesLooking ahead, Unisound will continue to deepen its "Strong Foundation Model + Deep Application" strategy. On the technological front, the Company will continue to increase strategic investment in foundational large models and strive to maintain a world-class level. On the application front, it will use the large-scale expansion of MaaS (Model-as-a-Service) and AI agents as its core growth engine, driving exponential growth in its AI in Daily Life and AI in Healthcare businesses. Meanwhile, the Company is actively exploring the establishment of a recurring revenue system through models such as API calls and Token-based billing, and regards opportunities in consumer-facing (C-end) products as a second growth curve to further expand its commercialization boundaries.Between Q2 and Q3 2026, Unisound will launch a native AI agent large model for programming and office applications, which is expected to double both intelligence density and token production efficiency. Copyright 2026 ACN Newswire. All rights reserved. www.acnnewswire.com
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Judge membantu mengatuan “Orwellian notion” menjadikan Anthropic sebagai risiko kewangan dan memperbolehkan Claude.

(SeaPRwire) - Seorang hakim federal telah memutuskan mendukung perusahaan kecerdasan buatan Anthropic dengan memblokir sementara Pentagon untuk melabeli perusahaan tersebut sebagai risiko rantai pasokan. Hakim Distrik AS Rita Lin pada Kamis mengatakan dia juga memblokir arahan Presiden Donald Trump yang memerintahkan semua lembaga federal untuk berhenti menggunakan Anthropic dan chatbotnya, Claude. Lin mengatakan "tindakan hukuman yang luas" yang diambil terhadap perusahaan AI itu oleh pemerintahan Trump dan Menteri Pertahanan Pete Hegseth tampak sewenang-wenang dan berubah-ubah dapat "melumpuhkan Anthropic," terutama penggunaan wewenang militer langka oleh Hegseth yang biasanya ditujukan pada musuh asing. "Tidak ada dalam undang-undang yang berlaku yang mendukung gagasan Orwellian bahwa sebuah perusahaan Amerika dapat dicap sebagai calon musuh dan penyabot AS karena menyatakan ketidaksepakatan dengan pemerintah," tulis Lin. Keputusan Lin menyusul sidang selama 90 menit di pengadilan federal San Francisco pada hari Selasa di mana Lin mempertanyakan mengapa pemerintahan Trump mengambil langkah luar biasa untuk menghukum Anthropic setelah negosiasi mengenai kontrak pertahanan menjadi buruk karena upaya perusahaan untuk mencegah teknologi AI-nya digunakan dalam senjata otonom penuh atau pengawasan terhadap warga Amerika. Anthropic telah meminta Lin untuk mengeluarkan perintah darurat untuk menghilangkan stigma yang menurut perusahaan diterapkan secara tidak adil sebagai bagian dari "kampanye balas dendam yang tidak sah" yang memicu perusahaan yang berbasis di San Francisco itu untuk menggugat pemerintahan Trump awal bulan ini. Pentagon berargumen bahwa mereka seharusnya dapat menggunakan Claude dengan cara apa pun yang dianggap sah. Lin mengatakan putusannya bukan tentang debat kebijakan publik itu tetapi tentang tindakan pemerintah sebagai tanggapan atasnya. "Jika yang dikhawatirkan adalah integritas rantai komando operasional, Departemen Perang bisa saja berhenti menggunakan Claude. Alih-alih, tindakan-tindakan ini tampak dirancang untuk menghukum Anthropic," tulis Lin. Anthropic juga telah mengajukan kasus terpisah yang lebih terbatas yang masih tertunda di pengadilan banding federal di Washington, D.C. Lin menulis bahwa perintahnya ditunda selama seminggu dan tidak mewajibkan Pentagon untuk menggunakan produk Anthropic atau mencegahnya beralih ke penyedia AI lainnya.Artikel ini disediakan oleh penyedia konten pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberikan jaminan atau pernyataan sehubungan dengan hal tersebut. Sektor: Top Story, Daily News SeaPRwire menyediakan distribusi siaran pers real-time untuk perusahaan dan lembaga, menjangkau lebih dari 6.500 toko media, 86.000 editor dan jurnalis, dan 3,5 juta desktop profesional di 90 negara. SeaPRwire mendukung distribusi siaran pers dalam bahasa Inggris, Korea, Jepang, Arab, Cina Sederhana, Cina Tradisional, Vietnam, Thailand, Indonesia, Melayu, Jerman, Rusia, Prancis, Spanyol, Portugis dan bahasa lainnya.
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